ID A0A160T6A6_9CHLR Unreviewed; 2028 AA.
AC A0A160T6A6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 2.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Putative Alpha-2-macroglobulin domain protein {ECO:0000313|EMBL:CUS05059.2};
GN ORFNames=CFX0092_A3181 {ECO:0000313|EMBL:CUS05059.2};
OS Candidatus Promineifilum breve.
OC Bacteria; Chloroflexota; Ardenticatenia; Candidatus Promineifilales;
OC Candidatus Promineifilaceae; Candidatus Promineifilum.
OX NCBI_TaxID=1806508 {ECO:0000313|EMBL:CUS05059.2, ECO:0000313|Proteomes:UP000215027};
RN [1] {ECO:0000313|EMBL:CUS05059.2, ECO:0000313|Proteomes:UP000215027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Cfx-K {ECO:0000313|EMBL:CUS05059.2,
RC ECO:0000313|Proteomes:UP000215027};
RA Oliw E.H.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protease inhibitor I39 (alpha-2-
CC macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
CC {ECO:0000256|ARBA:ARBA00010556}.
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DR EMBL; LN890655; CUS05059.2; -; Genomic_DNA.
DR KEGG; pbf:CFX0092_A3181; -.
DR OrthoDB; 9767116at2; -.
DR Proteomes; UP000215027; Chromosome i.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 1.50.10.20; -; 1.
DR Gene3D; 2.20.130.20; -; 1.
DR Gene3D; 2.60.40.1930; -; 1.
DR Gene3D; 2.60.40.3710; -; 3.
DR InterPro; IPR011625; A2M_N_BRD.
DR InterPro; IPR021868; Alpha_2_Macroglob_MG3.
DR InterPro; IPR041246; Bact_MG10.
DR InterPro; IPR001599; Macroglobln_a2.
DR InterPro; IPR002890; MG2.
DR InterPro; IPR032812; SbsA_Ig.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR40094; ALPHA-2-MACROGLOBULIN HOMOLOG; 1.
DR PANTHER; PTHR40094:SF1; UBIQUITIN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00207; A2M; 1.
DR Pfam; PF07703; A2M_BRD; 1.
DR Pfam; PF13205; Big_5; 4.
DR Pfam; PF17973; bMG10; 1.
DR Pfam; PF11974; bMG3; 1.
DR Pfam; PF01835; MG2; 1.
DR SMART; SM01360; A2M; 1.
DR SMART; SM01359; A2M_N_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000215027};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 1093..1242
FT /note="Alpha-2-macroglobulin bait region"
FT /evidence="ECO:0000259|SMART:SM01359"
FT DOMAIN 1314..1404
FT /note="Alpha-2-macroglobulin"
FT /evidence="ECO:0000259|SMART:SM01360"
FT REGION 1277..1303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2028 AA; 217292 MW; E8A20D8A0CE70495 CRC64;
MSSRHITRSL LILVAFLLLL AACRRGQPEA VPTLASPAEI EPTEAAAPAE PTAEPAAEAE
PTAAPIVARP VPVEDIDWPP QVIASDPRPG QEVGLETPIT VRFDQPMDQS SVEAAFTLDP
PVAGELSWPE PDTAVFTPAE PLELGQTYNV RIADSAGAAN GQTLSQPVEF AIQATGPLQV
TQVIPADNAG TVQTDAIITV VFDKPVVPLL SSGEQSGLPQ PLTFDPPATG TGEWTATSIY
RFMPDPPLAG ATTYTVSVDP ALTDLTGSPL ADAPTWSFTT LPPDVVLTEP ENEKARVAPD
ASILVIFNMP MDMGGVEAAT SLANSDGAAV PVTFAWRDNR SVDITPVDPL PLGDEYTLTV
AAAATDINGA ATMEDDHVST FSTIPLPAIL NTYPADGAVA DMFGNGFSIE FASPMNDETI
EDQLIITPTP EDVDYFISQW DEGYSVYVQF TLTPDTEYTV TVPASAADPY GNTLGEDFTF
TFTAAPIPPM ASFNLPREVA QLSTSFPSDV QVLSRNIGEV TVELYDIGVD TNLVFNTYLM
YEQEPTGEPI FRTTITPTGP ADELSVSPVQ LAAGGVLPTG LYRLRVTSPE LSSDTNWWQN
RNVLLVVGDT NLVIKEMYGE VNVWATDLAT GEPVGGLDLT LYRRSGEEAG TAVTDANGFA
RFDYDPAESY LEGVAVVANE PGAPGFGLAS TLWTGNISVW NLGLTVDTGP EQALFAYIYT
DRPIYRPGDT VFFKGIVRHP QFGRYELPDV TELELSVNPN FFMGEEGFSE TFTVTLDEDG
VFAGEFALPD DMPLGTYSFN ITGDFWLSSR TFTVAEYRAP EFEVLVTPEQ PELLRGAATN
VTVNATYLFG GSAAGLPVTW NITAVEFVPT FEVNPPFTFG DSADFNYVVD PFVFGGGGLE
ENVGSGNGET DAAGNVTIPL PAEMLDELEA GSRQVTVEAT VGGLGEFPVT GRATVTFHSA
DAYVGLRAAN TLVDAGDEVT IDLLSVDWAG EPLGNQAVEV VFYEREWESE RVAEFGMRTT
RWTPVDTEVG RQSVTTDAGG EATATFTPES GGMYLAVATL TDGGGRQQLS SLGLWSVDET
FAGWRTDPNM RTMEVTPDRN EYRAGETARV LVQSPFAQPV NAWLVIERGN IIDQQVVTVS
GSQVLEIPIT EAYAPNVHIT VVAIKPVDPA DADFPYADIR IGFAELTVPP DQFDLNVTIT
PGAEEYAPGD TATFDVVVTD QAGAPVQAEV SLSLVDLAVL LLKEDNAPHI LEAFYSPQPL
RSTIGSGLLV TGEGLEIEEP LPGGGGGGGG GADEGLESLR LPGEDDVRRD FRDTAYWEAK
VLTDADGRVS VEVPLPDNVT TWRMHSKAAT TDTRVGQASA DILARLPLII RPVTPRFFTV
GDTLSLGANV NNNTDAAIEA TVTLEASGLA IDGPTEQTVT VPADGRVLVT WPVTVEDVAS
ADLTFRVAGG DYSDASKPTL GIGPDALLPI YRYDGRDFVA TAGELDEAGR RVEAVVLPQG
VNQTQGEVLV RLQPSLAAAI VESFEVINDP VVPFIECAGS LADRLLHNTA VEMAIRDLDL
DMADMATTLA ERNAADAAKL AALQMAGGGW GWCFSAESDP WISAQSLLAL TRAAELGYEV
DATVIDSGAE YVSGRLAPVN QLGDASEANR QAFFLYVVAQ AGEDILEDAD ELVAEHRALL
DPYAKALLAL AYDAAGATGD NQDALLTDLN DEVIMSATGA HWEDDETDFL NLSSDIRGTA
MVVEALAQLQ PDSPLLPPAV RWLMVARQAE TWSTLHTTAW SVSALSKWMA ASGELEPDYA
YELLVNLQSR AAGSFTPDDP TAAETVEIPL SELLTDDTNF FDFQRGEGDG RLYYTLRLNS
AIAVEQLDPI SRGFTVARRY FDAACDPATE TCEPIAGIAA GERVRVELTV IVPNDRVYVL
VEDPIPAGTD AIDPNLLTSE SGRGGSIVPA ENEFADGFWG WWYFDHIQYR DEKVVFLSQF
LPAGTYQYTY FLQPNIPGTY QVMPATARED YFPEVFGRSE GAIFTITE
//
