ID   A0A160VSQ7_9EURY        Unreviewed;       931 AA.
AC   A0A160VSQ7;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=FIG001454: Transglutaminase-like enzymes, putative cysteine proteases {ECO:0000313|EMBL:CUX77932.1};
GN   ORFNames=A3L04_09595 {ECO:0000313|EMBL:ASJ17303.1}, CHITON_1153
GN   {ECO:0000313|EMBL:CUX77932.1};
OS   Thermococcus chitonophagus.
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=54262 {ECO:0000313|EMBL:CUX77932.1, ECO:0000313|Proteomes:UP000093069};
RN   [1] {ECO:0000313|Proteomes:UP000093069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Vorgias C.E.;
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CUX77932.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=1 {ECO:0000313|EMBL:CUX77932.1};
RA   Oliw E.H.;
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:ASJ17303.1, ECO:0000313|Proteomes:UP000250189}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GC74 {ECO:0000313|EMBL:ASJ17303.1,
RC   ECO:0000313|Proteomes:UP000250189};
RA   Oger P.M.;
RT   "Complete genome sequence of Thermococcus chitonophagus type strain GC74.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP015193; ASJ17303.1; -; Genomic_DNA.
DR   EMBL; LN999010; CUX77932.1; -; Genomic_DNA.
DR   RefSeq; WP_068577600.1; NZ_LN999010.1.
DR   AlphaFoldDB; A0A160VSQ7; -.
DR   STRING; 54262.CHITON_1153; -.
DR   GeneID; 33322834; -.
DR   KEGG; tch:CHITON_1153; -.
DR   OrthoDB; 18481at2157; -.
DR   Proteomes; UP000093069; Chromosome i.
DR   Proteomes; UP000250189; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.620.30; -; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   PANTHER; PTHR42736; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   PANTHER; PTHR42736:SF1; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   Pfam; PF01841; Transglut_core; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:CUX77932.1};
KW   Membrane {ECO:0000256|SAM:Phobius}; Protease {ECO:0000313|EMBL:CUX77932.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        773..795
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          247..315
FT                   /note="Transglutaminase-like"
FT                   /evidence="ECO:0000259|SMART:SM00460"
FT   REGION          314..333
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        318..333
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   931 AA;  104007 MW;  DF5187DBEC75FEC7 CRC64;
     MKGVKEVLSA LIIGIAGLLI LSASIPQGLV PNLAQNIQEN EHDIDLRENA IRSALLNNTP
     VMVVYEERGI VEYLRQNVYY RYENGRWTGE QQFKGVSVFG YVPIFKPTNP HKTLTDKITV
     EMRSPLISGN IYTALYTARL SIPAIYSEEY IIFRPSRYPV QSYEFEVEKY EFPPNILKNA
     SVPEIKKYLQ TPKLSTRVYE LAKNITRGIS SPYEKALAIE RFLKQNYIYD ETAPPAPPGI
     DPVEWFLFYS KRGVCLDFNT AFVILARING LPARLVTGFR VEPKPGKQEV LLKQAHAWAE
     VYFNGLGWVT FDATGSPRQS KGKKEQQRPR EETIPEVRIP LGESRTVALQ VKSKNISVNS
     PLPVTLHRHG DQVILNITGT KVGKFKLVIV ADTKNITVPV IVGYKTIVRI TEWPHEVRTG
     ANFTVKGIVT TLSGAPVPVG SVRIELRKDK RTPGKIIGRG RVVNGKFNVT CSAAGVAGKY
     QLVAIYEGGE VYFPSVSDPE IVIKDKAKIY VNKFNYTKVG PIKIEGFLGT EGGAFLSEEP
     IEIILDGKLL GVARTDKNGK FSFSFVLTSP GLHNLTILYS GQEGVEGDSE TITFRAIEAS
     ISIPALADAG DYLKITGQIE GIKSGRLKIT GDFGEYSVSI NNEGHFKVEI PVPRNFEGYK
     RVAVYYEDLL LAEKYVYVRQ KIIVEASGTI MVAKKPNDLI IRVRYTNGTP VSRARIVLTA
     FNSTFVNFTD EMGISKFVLT PPSPGTYPLD VMVITSNGFE VTPIKVRVYK YPIYVYIALA
     ALIVSLGAFS IRALLTHEVL KIFTTRDPPI YVNREEISVT SNVPISLYVD GKFYAKGKEF
     TLKLSPGNHE IWGKFLLFRS KPLRIKVCKN REEAIIEAFE KCADGEPSKT AREILGVNKI
     VLIFEKVRYG LKSASVKEFL EFIKSACRRD I
//