ID A0A161JH58_STRLU Unreviewed; 344 AA.
AC A0A161JH58;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Dihydrolipoamide S-succinyltransferase {ECO:0000313|EMBL:BAU82712.1};
GN ORFNames=SLA_1774 {ECO:0000313|EMBL:BAU82712.1};
OS Streptomyces laurentii.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=39478 {ECO:0000313|EMBL:BAU82712.1, ECO:0000313|Proteomes:UP000217676};
RN [1] {ECO:0000313|EMBL:BAU82712.1, ECO:0000313|Proteomes:UP000217676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31255 {ECO:0000313|EMBL:BAU82712.1,
RC ECO:0000313|Proteomes:UP000217676};
RA Doi K., Fujino Y., Nagayoshi Y., Ohshima T., Ogata S.;
RT "Complete Genome Sequence of Thiostrepton-Producing Streptomyces laurentii
RT ATCC 31255.";
RL Genome Announc. 4:e00360-16(2016).
CC -!- COFACTOR:
CC Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC Evidence={ECO:0000256|ARBA:ARBA00001938};
CC -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00007317}.
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DR EMBL; AP017424; BAU82712.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A161JH58; -.
DR KEGG; slau:SLA_1774; -.
DR Proteomes; UP000217676; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 4.10.320.10; E3-binding domain; 1.
DR InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR InterPro; IPR014276; 2-oxoglutarate_DH_E2.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR036625; E3-bd_dom_sf.
DR InterPro; IPR004167; PSBD.
DR NCBIfam; TIGR02927; SucB_Actino; 1.
DR PANTHER; PTHR43178; DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; 1.
DR PANTHER; PTHR43178:SF5; LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL; 1.
DR Pfam; PF00198; 2-oxoacid_dh; 1.
DR Pfam; PF02817; E3_binding; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
DR SUPFAM; SSF47005; Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex; 1.
DR PROSITE; PS51826; PSBD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000217676};
KW Transferase {ECO:0000313|EMBL:BAU82712.1}.
FT DOMAIN 38..75
FT /note="Peripheral subunit-binding (PSBD)"
FT /evidence="ECO:0000259|PROSITE:PS51826"
SQ SEQUENCE 344 AA; 35231 MW; 57ABECCE1A389C96 CRC64;
MAPAAPAAPA PAPVATPAPV TPAPAPAVVA EPAEDGAYVT PLVRKLASEN GVDLSAVKGS
GVGGRIRKQD VLAAAEAKKA APAPVAAPVA AATPAAKAPA LEVSPLRGQT VKMTRMRKVI
GDNMFKALHT QAQLTTAVEV DVTKLMKLRN QAKDAFAARE GVKLSPMPFF VKAAAQALKA
HPVINARINE DEGTITYFGT ENIAIAVDSE KGLMTPVIKG AGDLNIAGIS KATADLAAKV
RASKITPDEL SGGTFTISNT GSRGALWDTV IVPPSQVAIL GIGATVKRPA VIETAEGTVI
GVRDIVVLAL SYDHRLVDGA DAARYLNAVK AILEAGEFEV DLGL
//
