ID A0A161LVE5_9ACTN Unreviewed; 622 AA.
AC A0A161LVE5;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Putative glycosyl hydrolase {ECO:0000313|EMBL:GAT65821.1};
GN ORFNames=PS9374_01465 {ECO:0000313|EMBL:GAT65821.1};
OS Planomonospora sphaerica.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Planomonospora.
OX NCBI_TaxID=161355 {ECO:0000313|EMBL:GAT65821.1, ECO:0000313|Proteomes:UP000077701};
RN [1] {ECO:0000313|EMBL:GAT65821.1, ECO:0000313|Proteomes:UP000077701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 9374 {ECO:0000313|EMBL:GAT65821.1,
RC ECO:0000313|Proteomes:UP000077701};
RA Dohra H., Suzuki T., Inoue Y., Kodani S.;
RT "Draft Genome Sequence of Planomonospora sphaerica JCM9374, a Rare
RT Actinomycete.";
RL Genome Announc. 4:e00779-16(2016).
RN [2] {ECO:0000313|Proteomes:UP000077701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 9374 {ECO:0000313|Proteomes:UP000077701};
RA Suzuki T., Dohra H., Kodani S.;
RT "Planomonospora sphaerica JCM9374 whole genome shotgun sequence.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAT65821.1}.
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DR EMBL; BDCX01000003; GAT65821.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A161LVE5; -.
DR STRING; 161355.PS9374_01465; -.
DR Proteomes; UP000077701; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd18616; GH43_ABN-like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR041542; GH43_C2.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF5; ENDO-ARABINASE; 1.
DR Pfam; PF17851; GH43_C2; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:GAT65821.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000077701};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..622
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007824863"
FT DOMAIN 429..522
FT /note="Beta-xylosidase C-terminal Concanavalin A-like"
FT /evidence="ECO:0000259|Pfam:PF17851"
FT REGION 33..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 397..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 88
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 270
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 222
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 622 AA; 66899 MW; 014323F76BBA0309 CRC64;
MGARVVRRMI VTLAGLACLL AAAPAAEAAD PARAEAADPA SAPEAAGRSP ASSGRAPAGP
DAGGPAAGRG PGTYTNPVSG SFSDTFADPA IVRGEDGWWY AFGTSDPLRE GEGTRHHLPV
SRSRNLVDWS YIGDAFTERT LPAWADTAAG ASLWAPDIRR VDGEYRLYYV VTQTTVTPEP
GDNAIGMATA PTPAGPWTDS GAPVVGPRRG AGASGDFKWT FDPAHAVDTD GTEYLVYGSY
YGGIFITRLD PTGRRAVGEP TMIAIDNKFE GGYLVRRGGY WYLFASSADC CAGPTTGYSV
YAGRSRAITG PYLDREKVPL VTSRAGGTIV IAPNGNRWVG TGHNAVVTDP AGQDWLVYHA
IDRADPYLDE PFGINERPML IDRLDWIDGW PTVRGGAWAS EDPQRAPGRT GPVKVAPTPR
PGPVDRRRSD EFDGTGLGSG WSWVRGPQGE VTGGALRWPT QAAELNREDN TASVLLREVP
EGDWTAETRL RIDLGTDSVR NYQQAGLIAY AGDDLYTKLV HAAIWNTRQT EFGKEMPYEG
RIAYGGTIVG PPAEETWLRL IHRVDRRNGE HELRAATSRD GRRWVFGGVW TLPADADLRV
GLISLGGAGA TAEFDYFRLH RR
//
