ID A0A161USW0_9NOCA Unreviewed; 618 AA.
AC A0A161USW0;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Propionyl-CoA synthetase {ECO:0000313|EMBL:KZF03522.1};
GN Name=prpE {ECO:0000313|EMBL:KZF03522.1};
GN ORFNames=A2J03_07655 {ECO:0000313|EMBL:KZF03522.1};
OS Rhodococcus sp. EPR-157.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=1813677 {ECO:0000313|EMBL:KZF03522.1, ECO:0000313|Proteomes:UP000077673};
RN [1] {ECO:0000313|EMBL:KZF03522.1, ECO:0000313|Proteomes:UP000077673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EPR-157 {ECO:0000313|EMBL:KZF03522.1,
RC ECO:0000313|Proteomes:UP000077673};
RA Ploux O.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZF03522.1}.
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DR EMBL; LVCV01000437; KZF03522.1; -; Genomic_DNA.
DR RefSeq; WP_068377661.1; NZ_LVCV01000437.1.
DR AlphaFoldDB; A0A161USW0; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000077673; Unassembled WGS sequence.
DR CDD; cd05967; PrpE; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000077673}.
FT DOMAIN 5..54
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 61..439
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 504..582
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 618 AA; 66648 MW; F126550A2A4F8EB8 CRC64;
MSGEYRNAFD SSISDREGFW LEAAGGIDWT TPPTSAFTNG RWFEDGELNT CVNALDRHVD
AGHGDRTALI YDSAMLGTVR SFTYSELLDE VALFAGVLVK NGVTVGDRVV LYLPMIPEAV
VAMLACARIG AVHSVVFGGF AAKELAARID DAEPALLITA SGGFEPGKVI EYLPIVEKAL
ALTTAPKPTV IVKAREGIGN THSWLDWDEQ LVDTVAAEPV SVRATDPLYI LYTSGTTGKP
KGVVRDNGGH AVALMWSMRN IYDVGEGQVM WTASDVGWVV GHSYIVYGPL LAGATSVLYE
GKPVGTPDAG AFWRVIQDHG VRALFTAPTA LRAIRKVDPR ASELEKYDIS SLATVFVAGE
RLDPDTYEWV SRTLDRPVVD HWWQTETGWA ICANLRGLEP LPIKSGSPTV AVPGFQVGIL
DARGAEVDAG TEGNIVVKLP LPPGTLVGLW NDEDRFRRSY LETFPGYYLT GDSGYIDADG
YVYVLGRSDD VINVAGHRLS TGSMEAVVAS HPAVAECAVI GIHDELKGQR PSGYVVLKAG
ESIEEEQLRT ELVAMVRDQI GALATFRDVT IVGALPKTRS GKILRKTMRQ IVAGEEYGVP
STIEDPAVLD ALEKLLGR
//
