ID   A0A161Y4I2_9PEZI        Unreviewed;       363 AA.
AC   A0A161Y4I2;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=2-hydroxyacid dehydrogenase {ECO:0000313|EMBL:KZL66617.1};
GN   ORFNames=CT0861_08019 {ECO:0000313|EMBL:KZL66617.1};
OS   Colletotrichum tofieldiae.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC   Colletotrichum spaethianum species complex.
OX   NCBI_TaxID=708197 {ECO:0000313|EMBL:KZL66617.1, ECO:0000313|Proteomes:UP000076552};
RN   [1] {ECO:0000313|EMBL:KZL66617.1, ECO:0000313|Proteomes:UP000076552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=0861 {ECO:0000313|EMBL:KZL66617.1,
RC   ECO:0000313|Proteomes:UP000076552};
RA   Hacquard S., Kracher B., Hiruma K., Weinman A., Muench P., Garrido Oter R.,
RA   Ver Loren van Themaat E., Dallerey J.-F., Damm U., Henrissat B.,
RA   Lespinet O., Thon M., Kemen E., McHardy A.C., Schulze-Lefert P.,
RA   O'Connell R.J.;
RT   "Survival trade-offs in plant roots during colonization by closely related
RT   pathogenic and mutualistic fungi.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KZL66617.1}.
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DR   EMBL; LFIV01000169; KZL66617.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A161Y4I2; -.
DR   STRING; 708197.A0A161Y4I2; -.
DR   OrthoDB; 1775226at2759; -.
DR   Proteomes; UP000076552; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   CDD; cd12163; 2-Hacid_dh_5; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR029752; D-isomer_DH_CS1.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076552}.
FT   DOMAIN          129..198
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF02826"
FT   DOMAIN          225..326
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF02826"
SQ   SEQUENCE   363 AA;  40952 MW;  AEADEF66C018D141 CRC64;
     MGDIAERTSP LARDVLLLVL SAPENPTWRR RVLERFPGLE VRWVDSRKPG GGYTSPDEVP
     DEVWEGVTIF YSYLPASPKR MSKVRFVQVS SAGVDMWVDH EVYKNPNVAF CTTNGCQSPQ
     IAEWVIGTWL SSQHHFLRYA NNMKEGFWES PMAVDIEDSV SLRMGILGYG AIGRQCGKIA
     QAMGMEVYAY TRSERSTPES RKDDSYCIPG TGDPDGLIPA KWFHGASKES INNFLNQDLD
     ILVLGLPLTK ETRGFFGKEQ FEILSKRKTF VSNIARGALV QNDALIEALE TGKIRAAAVD
     VTDPEPLPKD HPLWKAPNIF ITPHVSWRTK VHFERVLGLL ETNLERLHTE KPLINPVNRD
     LHY
//