ID   A0A161ZQP3_9EURY        Unreviewed;       334 AA.
AC   A0A161ZQP3;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=HTH iclR-type domain-containing protein {ECO:0000259|Pfam:PF09339};
GN   ORFNames=A4G99_22735 {ECO:0000313|EMBL:KZN26148.1};
OS   Haladaptatus sp. R4.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haladaptataceae; Haladaptatus.
OX   NCBI_TaxID=1679489 {ECO:0000313|EMBL:KZN26148.1, ECO:0000313|Proteomes:UP000076599};
RN   [1] {ECO:0000313|EMBL:KZN26148.1, ECO:0000313|Proteomes:UP000076599}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R4 {ECO:0000313|EMBL:KZN26148.1,
RC   ECO:0000313|Proteomes:UP000076599};
RA   Mukhopadhyay S.K.;
RT   "Genome sequence of halophilic archaea.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KZN26148.1}.
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DR   EMBL; LWHG01000005; KZN26148.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A161ZQP3; -.
DR   OrthoDB; 248536at2157; -.
DR   Proteomes; UP000076599; Unassembled WGS sequence.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 4.10.1080.10; TSP type-3 repeat; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR   InterPro; IPR028974; TSP_type-3_rpt.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR37467; EXPORTED CALCIUM-BINDING GLYCOPROTEIN-RELATED; 1.
DR   PANTHER; PTHR37467:SF1; EXPORTED CALCIUM-BINDING GLYCOPROTEIN-RELATED; 1.
DR   Pfam; PF09339; HTH_IclR; 1.
DR   Pfam; PF18884; TSP3_bac; 8.
DR   SUPFAM; SSF103647; TSP type-3 repeat; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   4: Predicted;
FT   DOMAIN          264..305
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000259|Pfam:PF09339"
FT   REGION          1..189
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          236..256
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..38
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        86..117
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        135..168
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        175..189
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   334 AA;  35860 MW;  0C22F7A844402720 CRC64;
     MVKTGDDDGD DLTNKKEIKL GTNVTSKDTD KDGLEDGEEV NNYGTNATKA DTDGDGLRDR
     QEISIGSNPT QEDTDADGLS DKREYELGTN VSNADTDGDG LTDVSEVNGT TKPTMADSDK
     DGLNDSVEVA GATDPMKPDT DEDGLEDGKE KKLGTDPTKA DTDGDGLSDG TEQKLGTDPL
     KRDTDGDGLS DGFEHSFGTN PNSRVLTGGL YLVFLSLLVG MALLVQRNGT EWLPTLLGGE
     SSRDGEPKPE PHLQDGKVTT DADRVLKLLR ENGGRLPQGE IIERTGWSKS KVSRLLSKME
     DRKQVSKINI GRKNIVILYG QEPGNTNNTS EKPQ
//