ID A0A161ZUN1_9BACI Unreviewed; 330 AA.
AC A0A161ZUN1; A0A161W1F5;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Pyruvate dehydrogenase (Acetyl-transferring) E1 component subunit alpha {ECO:0000313|EMBL:KZN96967.1};
GN ORFNames=AP3564_02665 {ECO:0000313|EMBL:ASS89298.1}, AZI98_05210
GN {ECO:0000313|EMBL:KZN96967.1};
OS Aeribacillus pallidus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Aeribacillus.
OX NCBI_TaxID=33936 {ECO:0000313|EMBL:KZN96967.1, ECO:0000313|Proteomes:UP000076476};
RN [1] {ECO:0000313|EMBL:KZN96967.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=8m3 {ECO:0000313|EMBL:KZN96967.1};
RA Poltaraus A.B., Nazina T.N., Tourova T.P., Malakho S.M., Korshunova A.V.,
RA Sokolova D.S.;
RT "Draft genome sequence of Aeribacillus pallidus 8m3 from petroleum
RT reservoir.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ASS89298.1, ECO:0000313|Proteomes:UP000214606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC3564 {ECO:0000313|EMBL:ASS89298.1,
RC ECO:0000313|Proteomes:UP000214606};
RA Lee Y.-J., Park M.-K., Yi H., Bahn Y.-S., Kim J.F., Lee D.-W.;
RT "The whole genome sequencing and assembly of Aeribacillus pallidus KCTC3564
RT strain.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; CP017703; ASS89298.1; -; Genomic_DNA.
DR EMBL; LWBR01000013; KZN96967.1; -; Genomic_DNA.
DR RefSeq; WP_063387224.1; NZ_QURG01000031.1.
DR STRING; 33936.AZI98_05210; -.
DR KEGG; apak:AP3564_02665; -.
DR OrthoDB; 9766715at2; -.
DR Proteomes; UP000076476; Unassembled WGS sequence.
DR Proteomes; UP000214606; Chromosome.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR11516:SF60; PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA; 1.
DR PANTHER; PTHR11516; PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Pyruvate {ECO:0000313|EMBL:KZN96967.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076476}.
FT DOMAIN 22..319
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 330 AA; 35846 MW; D3C45289E5ADC724 CRC64;
MTIAKSTSTP ITQEKAKWIF QKMHEIRQFE DKVHEIFSKG VLPGFVHLYA GEEAVAVGIC
AHLDDKDYIT STHRGHGHCI AKGCDLNGMM SEIYGKATGL CNGKGGSMHI ADVEKGMLGA
NGIVGGGFPL AVGAGLTAKL KKSGAVAVCF FGDGANNHGT FHEGINLAAI WKLPVVFVAE
NNGYAEATPF EYASSCKNIA DRAQAYNIPG EVVDGKDVVA VYEAAERAVA RARNGEGPTL
IECKTYRNYG HFEGDAQTYK SAEEKQKHLQ ENDAIAKFRH YILSNQLISE QELLNIEQQV
TKAVEEAVHF AEKSPFPSAE DLLKDVYVSY
//
