ID A0A162A5N7_DAUCS Unreviewed; 375 AA.
AC A0A162A5N7;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Chalcone synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=DCAR_018992 {ECO:0000313|EMBL:KZM95750.1};
OS Daucus carota subsp. sativus (Carrot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Apiales; Apiaceae; Apioideae; Scandiceae; Daucinae;
OC Daucus; Daucus sect. Daucus.
OX NCBI_TaxID=79200 {ECO:0000313|EMBL:KZM95750.1};
RN [1] {ECO:0000313|EMBL:KZM95750.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaf {ECO:0000313|EMBL:KZM95750.1};
RX PubMed=27158781; DOI=10.1038/ng.3565;
RA Iorizzo M., Ellison S., Senalik D., Zeng P., Satapoomin P., Huang J.,
RA Bowman M., Iovene M., Sanseverino W., Cavagnaro P., Yildiz M.,
RA Macko-Podgorni A., Moranska E., Grzebelus E., Grzebelus D., Ashrafi H.,
RA Zheng Z., Cheng S., Spooner D., Van Deynze A., Simon P.;
RT "A high-quality carrot genome assembly provides new insights into
RT carotenoid accumulation and asterid genome evolution.";
RL Nat. Genet. 48:657-666(2016).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|RuleBase:RU003633}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZM95750.1}.
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DR EMBL; LNRQ01000005; KZM95750.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A162A5N7; -.
DR STRING; 79200.A0A162A5N7; -.
DR EnsemblPlants; KZM95750; KZM95750; DCAR_018992.
DR Gramene; KZM95750; KZM95750; DCAR_018992.
DR Proteomes; UP000077755; Chromosome 5.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 3.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877:SF57; CHALCONE SYNTHASE; 1.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003633};
KW Reference proteome {ECO:0000313|Proteomes:UP000077755};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003633}.
FT DOMAIN 9..229
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 313..372
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 168
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 375 AA; 41443 MW; BDD3C33B839EA789 CRC64;
MAASSLSVEE IMKNQRAKGP ATVLAIGTAA PPNCYPQADY PDFYFRVTKS EHMTQLKEKF
KRICNKSKIE TRYLHITEET LEENPNMCHY SAPSFDARQE ILRMEVPKLG KEAADKAIKE
WGHSKSEITH LIFCTTSGYD MPSADYQLTK LLGLNNSVKR HMVYLQGCFA GGTVLRLAKD
LAENNKGARV LVVCSEITTI TFRGPHIHSL LPQALFGDGA SSVIVGSDPD PLTERPLFQI
VFAAQHLVPD SEDTVRGKLG ESGLMFFLKR NITTLFAGNM EKILKEVFEP LGITDWNSLF
YITHPGGPAI LNQVLSEYGN MAGACVFFVM DEMRKKSMND GRATTGDGLD WGVALGFGPG
FTVETVVLHS MPVTH
//
