ID A0A162AAD0_DAUCS Unreviewed; 974 AA.
AC A0A162AAD0;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Homeobox domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DCAR_014738 {ECO:0000313|EMBL:KZM97900.1};
OS Daucus carota subsp. sativus (Carrot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Apiales; Apiaceae; Apioideae; Scandiceae; Daucinae;
OC Daucus; Daucus sect. Daucus.
OX NCBI_TaxID=79200 {ECO:0000313|EMBL:KZM97900.1};
RN [1] {ECO:0000313|EMBL:KZM97900.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaf {ECO:0000313|EMBL:KZM97900.1};
RX PubMed=27158781; DOI=10.1038/ng.3565;
RA Iorizzo M., Ellison S., Senalik D., Zeng P., Satapoomin P., Huang J.,
RA Bowman M., Iovene M., Sanseverino W., Cavagnaro P., Yildiz M.,
RA Macko-Podgorni A., Moranska E., Grzebelus E., Grzebelus D., Ashrafi H.,
RA Zheng Z., Cheng S., Spooner D., Van Deynze A., Simon P.;
RT "A high-quality carrot genome assembly provides new insights into
RT carotenoid accumulation and asterid genome evolution.";
RL Nat. Genet. 48:657-666(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class IV subfamily.
CC {ECO:0000256|ARBA:ARBA00006789}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZM97900.1}.
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DR EMBL; LNRQ01000004; KZM97900.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A162AAD0; -.
DR SMR; A0A162AAD0; -.
DR STRING; 79200.A0A162AAD0; -.
DR EnsemblPlants; KZM97900; KZM97900; DCAR_014738.
DR Gramene; KZM97900; KZM97900; DCAR_014738.
DR Proteomes; UP000077755; Chromosome 4.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR CDD; cd05157; ETNK_euk; 1.
DR CDD; cd00086; homeodomain; 1.
DR CDD; cd08875; START_ArGLABRA2_like; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR042160; GLABRA2/ANL2/PDF2/ATML1-like.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR PANTHER; PTHR45654:SF1; HOMEOBOX-LEUCINE ZIPPER PROTEIN HDG12; 1.
DR PANTHER; PTHR45654; HOMEOBOX-LEUCINE ZIPPER PROTEIN MERISTEM L1; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF01852; START; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00234; START; 1.
DR SUPFAM; SSF55961; Bet v1-like; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS50848; START; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000077755}.
FT DOMAIN 384..416
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 514..746
FT /note="START"
FT /evidence="ECO:0000259|PROSITE:PS50848"
FT DNA_BIND 386..417
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT COILED 425..492
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 974 AA; 110635 MW; 9CD36A0BF62ACB74 CRC64;
MGSVENEKKK DRLPSEATKI LQSLASGWDD IIDPNALQVI RVKGAMTNQV FQIKWPTRTE
RSRKVLVRIY GEGVDIFFDR ENEIRTFEFM SKMGRGPRLL GRFSNGRIEE FIHARTLSAA
DLRDPETSAL IATKMKEFHN LDMPGPKTVL LWDRLRNYLS VAKRMSSTEE ARDFGLNLIE
EELSFLENAL SSDHLTGFCH NDLQYGNIMI DEETSYITII DYEYACYNPI AYDIANHFCE
MAADYHTETP HLMDYSKYPG YDERKRFLRV YLSCSGKEPS DSELEHLIQE VEKYTLANHL
FWGLWGLISE LVNEIDFNYK EYARQRFQQY WLRKPELLGF STSSPIRANI MEVTGLAKKP
AGLPEGEVVD IIDTRLNKFK GSKDEARRLE LSVELGMTPS QIKFWFQNKR TQTKAKQEKE
KSIALRALND EIRGEINEIA QVLEALECRF CGKSCQVGEN IFINQQKLRA ENALLKEELE
RLSREVEEYT GMPISLHRAT EPSDHVLSNS SGVIATDKAF MVELAHHAME EFNTLLQSNE
FWMNSTDDGR TVIDLQAYER RFSRGPNSPN LRTESSKDCG VVFMNSLDLV EFFMDANKYM
EVFPTIVSKA RTIAVIKAGL MGNQNNLLQL MYEELNVLSP LVQTRKFCFL RFCKQLDQNS
WAIVDVSYDD PRESFDSQSQ VRRMPSGCYI QAMPDGQSKV TWMEHTRIED RASIHEFYRG
HIWSGLAFGA ERRLAVLKRM CERINCPLDY STPFFYIGGG RKNLMKLSQR MINGFCSSIN
PADGQQDMIS KIDDLEIHTT FRKCTDLVYP DSVVLSAAAT TWFPSAPLSI FNFLIDEKCR
PQWDVITDIG WVREAGRIGF HSGNCISLLE AFSTGQNKLI LQESWTDPSG ALVVYCPVPL
PAIKAVMSGE DPSILSLSPS GFVISGAMSG GALVTVLLQM SENSATPGSM SLESANLLNT
CVGITIDKLK AALS
//
