ID A0A162DAV5_9CRUS Unreviewed; 1123 AA.
AC A0A162DAV5;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=FHA domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=APZ42_026546 {ECO:0000313|EMBL:KZS09284.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS09284.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS09284.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS09284.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS09284.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS09284.1}.
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DR EMBL; LRGB01002081; KZS09284.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A162DAV5; -.
DR STRING; 35525.A0A162DAV5; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR CDD; cd22673; FHA_Ki67; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR029334; PP1-bd.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR21603; ANTIGEN KI-67-LIKE PROTEIN; 1.
DR PANTHER; PTHR21603:SF18; ANTIGEN KI-67-LIKE PROTEIN; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF15276; PP1_bind; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 38..92
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 820..1014
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT REGION 181..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 525..809
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 827..958
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 979..1123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..545
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..564
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 606..635
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 649..690
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 731..746
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 760..808
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 869..900
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 928..958
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 986..1000
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1018..1037
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1041..1069
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1123
FT /evidence="ECO:0000313|EMBL:KZS09284.1"
SQ SEQUENCE 1123 AA; 121610 MW; 290DDA2F603B3534 CRC64;
MADLSVKLPK PKYGQVVVLQ KNGDEPRGHG FPLISASCVV GRSTAADIRI SSADVSLTHC
IFTIDESSGE ASLEVRGNET QVNGTIVDPV NTIKLNHKDV VVIGGRKLRF EYLPPDYKPL
PSKPIPGVPS DSFNAEVVDL EENGDVVDSN AEKEEEVLQE VLSTPAAKRV SFGPYLSPEQ
FDNTLPPATP IKKGATPRRS TRYSGLKFTR SMIDPLVEED VTLESPSKEQ PVINSKECID
ETIISEDDAD ASVSSLAPAS ETAIVDSSPS LGIGVEFPEL SNSTNLEMSV DAMSTLSDVS
NIAAVPSECC SFLDEPIEED EFGPEVVEQE EESLSQMEDT SLFSEDIIGV EIPASAMTTS
RLTNGTELLR SFTTSSLAEN MGDEDEEEGI TLSPEDMSAV KNGHGSIIDS TTVLEVETQE
TPVPVKMKEI PSSPQVDDSD VGQVEHLVET QKLIPVTPKA DSASVGDAKQ LSQIPEADHL
LKKSKLAHDS TEGFAKVVET TAAVVVERVE QVDIININAD LEKVMETPES SPGKASLQTA
SPPTQEEEIE EVDAKKEVAA PRRGRKPAAA KTNTPKADYR DVKGVKRLLK TPTAATSTPQ
ADDSDVEDVD VLRKTPQAGD PEPEKAEEVN VPEGSSEKPA EEATAEANQS NEEEAKREEA
KREENAVYEP RLNVEEEAEV EKEATPPRRG RRAAPKSNTP KPGGRAKRKQ PLSDSDSQPE
SIGTADAPSA SEKEEQIDEE KADCPVKSAA KISTPKRSRR VPSTKVETPK AVRSTRGKRP
SESDSGQSEE VESRPLRSKR RKEEQLSEKL TLSPVVRLQR IDIAAEGTPS SERVAKVTRK
RGSVSSGEEW GVPEQVKPIR RGRGRPPKVV AHKTVEEEKA EEEPLRTATH KGKAAAVEEP
ISSDEELEDV EVKSTKKTTV GLRRAAVKRT SVPEKEEIAP EGKRRRGETR ATKHVTGLDD
VEMLHEGKGH AADIHANHMP DEVETNEESP VTSVKSGRST RAKSALKVHF DVAETAPSPV
RSTRSARKTT VATATPADKK VSVQLERDPD IETLAATAQE EEDKAPATKR SRHKKGLKAS
VTTMADESPA VPATIKRTRG GKKTTSEPEL HQQDTSAPPS PRR
//
