ID A0A162FPD0_9EURY Unreviewed; 344 AA.
AC A0A162FPD0;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=23S rRNA m(2) methyltransferase {ECO:0000313|EMBL:KZX13100.1};
GN ORFNames=MBORA_08500 {ECO:0000313|EMBL:KZX13100.1};
OS Methanobrevibacter oralis.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX NCBI_TaxID=66851 {ECO:0000313|EMBL:KZX13100.1, ECO:0000313|Proteomes:UP000077428};
RN [1] {ECO:0000313|EMBL:KZX13100.1, ECO:0000313|Proteomes:UP000077428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7256 {ECO:0000313|EMBL:KZX13100.1,
RC ECO:0000313|Proteomes:UP000077428};
RA Poehlein A., Seedorf H., Daniel R.;
RT "Genome sequence of Methanobrevibacter oralis DSM 7256.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZX13100.1}.
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DR EMBL; LWMU01000058; KZX13100.1; -; Genomic_DNA.
DR RefSeq; WP_042694847.1; NZ_LWMU01000058.1.
DR AlphaFoldDB; A0A162FPD0; -.
DR STRING; 66851.MBORA_08500; -.
DR PATRIC; fig|66851.6.peg.937; -.
DR OrthoDB; 7080at2157; -.
DR Proteomes; UP000077428; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0160102; F:tRNA (guanine(10)-N2)-methyltransferase activity; IEA:InterPro.
DR GO; GO:0030488; P:tRNA methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR InterPro; IPR005885; TrmG10.
DR NCBIfam; TIGR01177; TIGR01177 family methyltransferase; 1.
DR PANTHER; PTHR14911; THUMP DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR14911:SF13; TRNA (GUANINE(6)-N2)-METHYLTRANSFERASE THUMP3; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF143437; THUMP domain-like; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
DR PROSITE; PS01261; UPF0020; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KZX13100.1};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000313|EMBL:KZX13100.1}.
FT DOMAIN 51..153
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 344 AA; 39641 MW; A5B196CA8F1AAAA8 CRC64;
MELLCIQSQE HPFLPIAELK AVIECEEMEC NLEVIIKGLV IIKDIKAEKI NEYYKILIKR
LGYTHEIHQI IKKSTTNDLN EDVEDIDWSY YIKDTFAVRV KRFFSKIDTV ATERKVGSVI
LNNTRNIKVN LDKPTSLIRL VAFEDTVYIS IEKYKLDKKH FEDIKPHKRP FFYPGSMSPK
LARCMVNLSR VKKGDLLLDP FCGTGGILIE AGLIGCKVVG SDIYWKMKNG TAINLEFCGI
KDYKTFNLDV RELKMYEKVA SVVTDPPYGI STSTGNIDGD DIFKEFFNAI YDNMKDDAYL
CIASPHYVDL KPMMDEVGFK LVEEYEIKMH RSLTRIISVI RKNI
//
