ID A0A162K6Z5_CORDF Unreviewed; 560 AA.
AC A0A162K6Z5;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Major facilitator superfamily domain, general substrate transporter {ECO:0000313|EMBL:OAA77843.1};
GN ORFNames=LEL_04666 {ECO:0000313|EMBL:OAA77843.1};
OS Akanthomyces lecanii RCEF 1005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Akanthomyces;
OC Cordyceps confragosa.
OX NCBI_TaxID=1081108 {ECO:0000313|EMBL:OAA77843.1, ECO:0000313|Proteomes:UP000076881};
RN [1] {ECO:0000313|EMBL:OAA77843.1, ECO:0000313|Proteomes:UP000076881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCEF 1005 {ECO:0000313|EMBL:OAA77843.1,
RC ECO:0000313|Proteomes:UP000076881};
RX PubMed=27071652; DOI=10.1093/gbe/evw082;
RA Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT "Divergent and convergent evolution of fungal pathogenicity.";
RL Genome Biol. Evol. 8:1374-1387(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA77843.1}.
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DR EMBL; AZHF01000003; OAA77843.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A162K6Z5; -.
DR STRING; 1081108.A0A162K6Z5; -.
DR OrthoDB; 1701613at2759; -.
DR Proteomes; UP000076881; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR Gene3D; 1.20.1720.10; Multidrug resistance protein D; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23502; MAJOR FACILITATOR SUPERFAMILY; 1.
DR PANTHER; PTHR23502:SF51; QUINIDINE RESISTANCE PROTEIN 1-RELATED; 1.
DR Pfam; PF07690; MFS_1; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000076881};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 78..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 418..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 442..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 483..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 507..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 79..532
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 61894 MW; F14F4A2575DAEC1C CRC64;
MDRQASENIT KATSVPPEAS SDQNSERRIQ PAPQPMPSDV NSHDNKQAIS DQEGRQPGSP
EPAQAAPHSI FSRRTKMFII FMTVFATFFS PFSSFLYLPA ITPIAEAYHR SVGDINLTVT
LYQVMQAISP LFFGDLSDQI GRRPVYMATF TIYLAANIAL ALQNSYGALL FLRALQSTGS
SATVAIGNAV IADLTTPAER GGYITIVQAT IMFAPALAPV LGGILTQYLG WRSTFWFLVI
AAGVFIVLYV PLVPETARHI VGNGSIPPPT LNKSIISSVH WRRKRRDVEA NPGEEPFPEP
KKLPRRIPIP NIWAAIRIAF EKDVGLLLLF NSLLVMSNYA MLVPLQDVIR RRYHFNDLQV
GLCYIPYAIG NIIGALLMGK VLNWNYARVA RSLGMTPDRK RNDELRKFPI ERARTDPVWP
WVVLAIAMTA CWGWVVDSGA SLAAPLVVLF FQGVGVAGPM SALSTVLVDL YPSNAGRVSS
TFNLTRAAIS AVASAVIQLI IDAWGYGYTY LFLAMLLLVA SPSILCVRIW GPKWREERYV
RIEKQQAKEQ EKQAARQRAG
//
