ID A0A162KNB3_CORDF Unreviewed; 1357 AA.
AC A0A162KNB3;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Guanyl-nucleotide exchange factor {ECO:0000313|EMBL:OAA77468.1};
GN ORFNames=LEL_04291 {ECO:0000313|EMBL:OAA77468.1};
OS Akanthomyces lecanii RCEF 1005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Akanthomyces;
OC Cordyceps confragosa.
OX NCBI_TaxID=1081108 {ECO:0000313|EMBL:OAA77468.1, ECO:0000313|Proteomes:UP000076881};
RN [1] {ECO:0000313|EMBL:OAA77468.1, ECO:0000313|Proteomes:UP000076881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCEF 1005 {ECO:0000313|EMBL:OAA77468.1,
RC ECO:0000313|Proteomes:UP000076881};
RX PubMed=27071652; DOI=10.1093/gbe/evw082;
RA Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT "Divergent and convergent evolution of fungal pathogenicity.";
RL Genome Biol. Evol. 8:1374-1387(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA77468.1}.
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DR EMBL; AZHF01000003; OAA77468.1; -; Genomic_DNA.
DR STRING; 1081108.A0A162KNB3; -.
DR OrthoDB; 4248238at2759; -.
DR Proteomes; UP000076881; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF402; ARF GUANINE NUCLEOTIDE EXCHANGE FACTOR SYT1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000076881}.
FT DOMAIN 362..554
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT DOMAIN 681..810
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 956..1156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1196..1239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1271..1343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 880..907
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 45..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..77
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 956..972
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 993..1041
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1054..1094
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1104..1154
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1216..1230
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1301..1341
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1357 AA; 149942 MW; 14F3E17A9BB434C9 CRC64;
MPFLRRRGNL ASDSDTRQQD PISRSGKDAE MSTAAARSDG KATDLNDQAA ATTPRDSTTS
RPDTSHNHDD LSRQKRFSVL RFRNASDSQL SLKAKQQAEQ LPPLPSTPAI ITTAPTNDFN
GPRKVKSRMS LAAARFRRSN DIPRDSDQQS RPKSQKQAGK SFNDVRGRPT TATIDEPQSP
PLESRTSTAS NGTSLTTPAY RQSESSRSDA SSTDNAFLSS PNTTPKKTPA SSIFRLKRMR
KTPDSLFPLA HLPQKSKGGV VAQSASSLNV AATPRPASSQ SATTPKANLD GTDSRQGSQT
STIAALQTAA GRSGQSSPTR TSVLRGRSST MSSLGRNSTD DHLTLPQAGT STGRKSFGDL
LGISRLRQNS DLARQGTLTP LTPGSVPSNH NSFQLSRETV ILPDRKNDES ATKYLERLEA
DVPRGILAAS LAKSTDLFLS TVLRSYMRRF SFFGDPMDMA LRKLLMQAEL PKETQQIDRF
LQAFANRYHE CNPGIYSSPD QAYFIAFSLL ILHTDVFNKN NKHKMQKSDY IKNTRGEGIF
DDILECFYDN ISYTPFIHVE DDLDLGTERN ATIKSKRKPL IPGPGGDTAV RAAKEPIDPY
TLIFEGNLDL LRPNWKDAMC LEDHFNYLGT ATSLNMNDLQ KTFFRTGVLQ IISPRSRPDA
FMSEKTATNP QEAQQGIVDI KITKVGLLWR KDAKRRKTRS PWQEWGAILT GAQLYFFRNT
SWVKGLMHQY ENHIKAGHDE VPIIFNPPLS EFKPDVLMST HGAVALLDTT YKKHKNAFIY
VRQEGLDEVL LADNEDELND WLAKLNYAAA FRTSGVKMRG IVGGNYDGQG RRGMRRLDSS
DGIQLVQTPT GPVTIARGKI DHKMAEDIQI ARRRYMQVQI AESDQKVEEA QKQLEEQLRN
ARHLQILAPI QPRTRDSLLS AAARMSAQLK WTRMRIWKET CHRDILLQDF NEELPASPAL
STPNNKQDLE QAGSPTPKPP VVRTESKDNK HTTNENGPVT PTEPSITQFS NPQGTPKDGE
ASQENEVDAV SFTSAASPIR TPVSSPRPKW TRPQSEQESV RRKSTDLDEM DAEEQDLLRQ
AGLLERRRSK AADKANTALT DSTDALAERD RLERTKVRRS LQRTLRESAG HLSHHRSKRG
REPDSTRAED TGRESILSRG AGSFVVHGKK ASVITLGTEI QNMSNDDKIV ALKLQHQGDQ
PPSPSLSYGG DEDFHSAIDA SSEGAESRGR RESAASTNTA TALSFRELHR KYSSAQAARI
VSAGGRLAIP SDGESEVAVS FSDGRRSSLP PIETESEEED FEVNTKGKSV TEAAHDPKFE
NSLDSDRAGE EAEEKDAVDS SQDLAKLASR ALQVAEA
//
