ID A0A162KRL9_CORDF Unreviewed; 691 AA.
AC A0A162KRL9;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Acetoacetyl-CoA synthase {ECO:0000313|EMBL:OAA78818.1};
GN ORFNames=LEL_02304 {ECO:0000313|EMBL:OAA78818.1};
OS Akanthomyces lecanii RCEF 1005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Akanthomyces;
OC Cordyceps confragosa.
OX NCBI_TaxID=1081108 {ECO:0000313|EMBL:OAA78818.1, ECO:0000313|Proteomes:UP000076881};
RN [1] {ECO:0000313|EMBL:OAA78818.1, ECO:0000313|Proteomes:UP000076881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCEF 1005 {ECO:0000313|EMBL:OAA78818.1,
RC ECO:0000313|Proteomes:UP000076881};
RX PubMed=27071652; DOI=10.1093/gbe/evw082;
RA Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT "Divergent and convergent evolution of fungal pathogenicity.";
RL Genome Biol. Evol. 8:1374-1387(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA78818.1}.
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DR EMBL; AZHF01000002; OAA78818.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A162KRL9; -.
DR STRING; 1081108.A0A162KRL9; -.
DR OrthoDB; 45466at2759; -.
DR Proteomes; UP000076881; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000076881}.
FT DOMAIN 45..102
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 115..496
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 584..654
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 691 AA; 74536 MW; 26C94FA6322B48B3 CRC64;
MGQSVPQDPP ALAEKLWTHP DPSSTPMWRF IQRINNKYNL AIAGYPELYQ WSIDNVAEFW
SEAWHFVGIV ASKEAEQVLP KDAHMYPRPD FFGSARLNFA ENLLFPPTST PLDANATAVI
TTTELPGDLR STSWAELREA VRRCSNSLRA AGLRPNDVVA GYVSNHVEAL VAMLAAASIG
AVWTGISPDN GVSAVLDRLS QIGPKVLFAD NGTVYNGKEW SSTSKTDEIV AALKSTGLET
VVVINNIKGG LGLTELTAHG VKAVDYTSFL EIASTDALKF EQMPSSHPLY ILYSSGTTGL
PKAIVHTALG TLLQHKKEHV LHCSLTPASR MLYYTTTSWM MWHWSVGALA AGATLVLYSG
SPFRPNSYLS IPRVLSDLQV THFGTSAAYL TALEANNVRP VEDKSIDLSR LEAIYSTASP
LPPSTFKFVY EAFPKTVNLA SITGGTDIIS LFGAPCPLLP VRVGEIQCAG LGMAIKVVDS
ATGEDVPAGE PGDLVCVKPF PCQPLTFFGA NGEAKYQAAY FERFADVCGV QGAVWHHGDF
VKIPDASTGA LLMLGRSDGV LKPAGVRFGS AEIYNILTRF FAADVEDAVC VGRRRETDMD
ETVCLFVVPV EGKSFTEELQ GQIKAKIRSE LSPRHVPGVI AAAGGGIPKT GNGKKIEVAV
KQILSGMNIK TNASVANPES LEWFREWAKA N
//
