ID A0A162KTU4_CORDF Unreviewed; 2573 AA.
AC A0A162KTU4;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Beige/BEACH domain-containing protein {ECO:0000313|EMBL:OAA79758.1};
GN ORFNames=LEL_03244 {ECO:0000313|EMBL:OAA79758.1};
OS Akanthomyces lecanii RCEF 1005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Akanthomyces;
OC Cordyceps confragosa.
OX NCBI_TaxID=1081108 {ECO:0000313|EMBL:OAA79758.1, ECO:0000313|Proteomes:UP000076881};
RN [1] {ECO:0000313|EMBL:OAA79758.1, ECO:0000313|Proteomes:UP000076881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCEF 1005 {ECO:0000313|EMBL:OAA79758.1,
RC ECO:0000313|Proteomes:UP000076881};
RX PubMed=27071652; DOI=10.1093/gbe/evw082;
RA Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT "Divergent and convergent evolution of fungal pathogenicity.";
RL Genome Biol. Evol. 8:1374-1387(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA79758.1}.
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DR EMBL; AZHF01000002; OAA79758.1; -; Genomic_DNA.
DR STRING; 1081108.A0A162KTU4; -.
DR OrthoDB; 5478899at2759; -.
DR Proteomes; UP000076881; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR46108; BLUE CHEESE; 1.
DR PANTHER; PTHR46108:SF4; BLUE CHEESE; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000076881};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 1792..1925
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 1964..2256
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 2388..2429
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 923..955
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1117..1143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1716..1745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 925..955
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1716..1744
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2573 AA; 288802 MW; EB210EBBB0D24F0D CRC64;
MSTNTRRYRS STSASTPAAA NLKSTQVLRA LLDGLASQIN VSADNGYPEI TKLTKSLKDV
ADQISGPNTP TQQDAFRQAG GFEAVFNILR SFSGFYDPDK RSNKQMITLF QLLGATLDVL
AAALHSHSGN KRFFKFRVEG GGWEALEQAI ASIGLGGVEP NPWVSCHVFG KLFAFSLGDD
AIDLLFQSIA ETLRHDNERS ADQAEDTEPD DQWDLVLAKS MESIGPKVRE LVQSTTRVQY
PEMLRAIVSF WSSLPRDNDS AATPASLLVL ETILRAAEVL TYNCAAIHST GVMSQFLRVA
FSPNTPLTDS ERKKVMAICR RLMFFGVDKP ADTQFLLSVP GSEASEFCLE MMGKYHGPAF
FNFDLSLYGH SSLELPSLGR PFPPQSSPGY TFTAWIWIDH FDPAAHTTLF GAFDASQTCF
VLMYLERDTH NFILQTSVFS NKPSIRFKST EFRARQWYHI AIVHKRPRTM TASRAALYVN
GEFCEQMRCN YPLTPPLSNN SNESFASFNS GQNKTNPVQA FIGTPKELSG QLGTGLVSSR
WSLASAHLFD DVLGDDFLAV HYGLGPHYHG NFQDTLGGFQ TYEASAQLGL RNEIAHPGKD
ETSDILKAVR DKASVILPES RVLLSILPSA TLPENVQFLD TGLLRSLPRS AARALFMASN
KDGAPLAINS AVPNIADALF KPQGIASFRG SPTIALPSYL DENLWRLAGF TSLALKLLER
ATSVEETIRS LEIMFHCIRT SWRNSEAMER ENGYSILAML LRYKMGYASG LATEFFAIKL
YLSTEERDSL AFRVLSLVLG FVGYNHENPL DSLIVNPLAY RILLIDLDLW RKSAPRIQEL
YYKQFVTFAV NSKHHEFNNR RLIRMRIVKR LLDAMKGEAI PEEVLPHFMQ TFEVLVKSNL
GPEVMRSLSL FITYAFHVPS PPTSRALRPL SSVSRPTTPS LMRRQTGDGS GASSPLSGVK
YLTKKQLGTR VLSIYSRILC EKGNLNYIRK FAKTVTNKWL LYLLAENDKD ILLQGATILS
RLLVAHGSAY TSKFASKSAG FAIMANRLKR FWYSAALWPV VLSLMFGVDV AELDTDKWLD
TSHLLAVFGS RKVMYPDASV IITSMFQHGL NDGFKQDNNV SEPSLDPEHR PVSSAEPAKT
DTDEMTRAFQ TRMNIGKQAD PVFLQKMLNI FHELYEKSAD FRDFASASDW VRLILSMLYP
VVVSSDAVTP DVELHSRDST LNFDGSDVII RPIGLASGRP APIVRTTSVD LSATPQSTPP
KGTLLKRASS FVLLTKQAVQ EGEKQHDSMS RPLSSGGQSD DLVESLLGLA IKVFMDQIFK
RKEFSGFGLF TKVPPGSQEH QAYFESFLLK RIVTNSTELI MSNQAMLCEP KLITNMARLC
LHLTEAVFEG WFIDGAEVLI DFAGMLLEYL QRPDVASLKS VRLCSQSVTL IRTCLLRVIL
LKLSDLDRPE TAEAAAMEFM GKLAYWQMSI LGCFVAEDEY LKLFWYQLYT KLVDERGPVR
RSAANFLRIL LVAKPDASAA LIRSFMVPGQ KQVLHDFFKI TELDDDVFIA WVDQNRPSLD
SLFFGGMAKT WENFVSIENM RTQETAKTRF SKRRDKLKQW YVEGAAKDKL LADHETGNKG
WMKSIYNSEH FKYQRLLQDQ QDDLSFLISA YKKMEMDLRR PGAVFSDPRP LKWKLDRTEG
RNRMRLRLLP DFSTDMEKYR SKEKGVAAAA LRVNTAASNS PSAVPATPTL ATTPETTTPG
AATEADSELS LEQEDAGFAP EDDFELIEDP NDANDLDENF EDKNRKVMRR LEHGDQVQAA
YNVSRVTGLE ACEGILIIGK DALYMMDNVF QTATGDIVNV WQAPLEERDP FTRIVTGAKT
LEKRQTAGNR DQESRHWKWQ DTISISKRRF LFRDVAIEIF FTDGRSYLLT AINTAVRDEM
FAKMLSKAPH TSAAHALPNP EDAWRLEALK NFDESQQGIG SKLGTLFNTS SWNPLMKRWQ
KGEMSNFHYL MMVNTMAGRT FNDLTQYPVF PWVLADFTSE ELDLNDPASF RDLSKPMGAQ
TQERVQGFVE TYNALKEIEQ APFHYGTHYS SAMIVSSYLI RLPPFVQSYL LLQGDSFDHA
DRLFQSIPDA WKSASCRNKT DVRELIPEFF CLPEFLTNVN GYDFGRRQSN GVKVDNVVLP
PWAKGDPKIF IAKHREALES RYVSENLHRW IDLIFGFKQR GEAAVENLNV FHHLSYAGAS
DLDRITDANE RAITAGVIHN FGQTPHQAFT KPHPPRENAK CPVKRLDSSV QALICLPNPL
IESHERVASL IYARKLDRLL CASPFRLNLP PYDKFLEWGY ADNTVRFFFS DNRKPAGLFE
NLHIGQISCA GFADSKTLIT AGEDCVVSVY NVITSPGKTV ELVPKSSLFG HKTPITAIAV
SKSFSTFVSV SADGQGLLWD LNQLTFIRKL PLVRPVECAR INDVSGEILL CSGPSVILYT
LNGSVILDQN VCPDPDDYVH ACAFYEGAGN EWLENQLIFT GHSRGVVNIW RKSHSRARWS
LEHLRRLDHV DYKSDRRDNV SAGITCISPM PNCVYTGDED GRVFEWNFAG RDR
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