ID   A0A162M5F1_9HYPO        Unreviewed;      1217 AA.
AC   A0A162M5F1;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=GTPase activating protein {ECO:0000313|EMBL:OAA51130.1};
GN   ORFNames=BBO_01077 {ECO:0000313|EMBL:OAA51130.1};
OS   Beauveria brongniartii RCEF 3172.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Cordycipitaceae; Beauveria;
OC   Beauveria brongniartii.
OX   NCBI_TaxID=1081107 {ECO:0000313|EMBL:OAA51130.1, ECO:0000313|Proteomes:UP000076863};
RN   [1] {ECO:0000313|EMBL:OAA51130.1, ECO:0000313|Proteomes:UP000076863}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RCEF 3172 {ECO:0000313|EMBL:OAA51130.1,
RC   ECO:0000313|Proteomes:UP000076863};
RX   PubMed=27071652; DOI=10.1093/gbe/evw082;
RA   Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT   "Divergent and convergent evolution of fungal pathogenicity.";
RL   Genome Biol. Evol. 8:1374-1387(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAA51130.1}.
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DR   EMBL; AZHA01000002; OAA51130.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A162M5F1; -.
DR   OrthoDB; 22721at2759; -.
DR   Proteomes; UP000076863; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR   CDD; cd05137; RasGAP_CLA2_BUD2; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR039360; Ras_GTPase.
DR   InterPro; IPR023152; RasGAP_CS.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR10194:SF60; GTPASE-ACTIVATING PROTEIN; 1.
DR   PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR   Pfam; PF00616; RasGAP; 2.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
FT   DOMAIN          738..971
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   REGION          1..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          79..237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          370..393
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1144..1217
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..30
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        48..62
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..187
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1156..1177
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1217 AA;  134401 MW;  77F082A7B31F4D0D CRC64;
     MDGQTARPAA TSGEGQYNQT LQQPDLAATQ DTDLISDAVD ATPAALRSPF RSNATPATVN
     RASTPELAES LVSGTSYMSL DPIPVPRNPP AAPGSPRDIP GGFGRRRGIV FNDSFTDPSE
     LDSASPIAPK SSPVPARPRT RTLDGAIMSH RAALSSSDQR NRVGSISSSM PPAQTSLEDQ
     KQPPVAESVS YATPALPPRS LDTPSTPTST RDKRTGKRLL KHRPTSRPNS PIASLAPSVD
     SMSVPIAVED PNNLVSLMKT LCGRMRGQVE YQAEPGGAWY SGIAYVDEDA GSLMFDTNQS
     GSFHIPIVDD LRGCSVVPAE YTQGDRQCLE ITTPTPTHML LLPIIHDDLD LWLAALLSWQ
     QLRPNPIKFA NGKPASPTAP FRPDLRPFGK TPDETKPRNI IKIDKLMLWD KGAAPNPRAA
     FQRSSTRDIW SPSAAWRRVS CILHDTGELT LMLETDSIVL SHIDLTQLSR NAIQQLDRTV
     LDEEFCIAIF PTYAPKASRV SVFRPVYLAL DSRIHFEVWF VLLRAYAIPD LFHLGETEDD
     VLSNTLNSEI ENEGEIFRME KSVTVRITEA KIKTRPAGLE YVLPEKVHKM EHDPLIGNYL
     AEVILDGEVR ARTTTKCMTK NPFWREDCEF MDLAPSVQEL SVVLKRIEGM DGSRGAFPQE
     LICGTVHIAL DQLERGQSHE DWLQIRDEKQ QVIGSMLIRL SHDEHVALLA KEYEALSDTL
     HRFPTGLTTL ISAALPGQLK QLSELFLNIF QASGAASEWL LALVEDEIDG PGSQTSMKKY
     RFNSRLKSNE SIESPSDREL IVRDMSKSLA GEANLLFRGN TLLTQSFEFH MRRLGKEYLE
     EALRDKVFEI NEQNPDCEVD PSKLNGADLD QHWNQLIRIT SEIWQCIAQS AKRIPPELRH
     VLKYIRGVAE DRFGEFKRSA TYTAVSGFLF LRFICPAILA PKLCGLLRDF PRPKAQRTLT
     LVAKTLQKLS NLGTFGKREE YMEPMNRFLT SHRSVFREYI DQVCSIPSDR SVVAPPANYS
     TPNTICGRLS PTSREGLGSL PYLIDAPTSF AGLVKLWTSA GFDDLNTQHT DGELIIFNDL
     CLGLQKRVDA CMAKAGRLRA AEAAARGAPS RLVETLEQAA LAEPLRSPYS AAYTAMCHDV
     DQLFSGSGSD GPDEGSSSSR RSKDIRHGRD GHDGRKTGGF SSRGTPKGRN GKVGRTLLSG
     IMKIGGRAES PDFKNRQ
//