ID A0A162MBM3_9FIRM Unreviewed; 707 AA.
AC A0A162MBM3;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=HD/PDEase domain-containing protein {ECO:0000259|SMART:SM00471};
GN ORFNames=ATZ99_17590 {ECO:0000313|EMBL:KYO65170.1};
OS Thermovenabulum gondwanense.
OC Bacteria; Bacillota; Clostridia; Thermosediminibacterales;
OC Thermosediminibacteraceae; Thermovenabulum.
OX NCBI_TaxID=520767 {ECO:0000313|EMBL:KYO65170.1, ECO:0000313|Proteomes:UP000075737};
RN [1] {ECO:0000313|EMBL:KYO65170.1, ECO:0000313|Proteomes:UP000075737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R270 {ECO:0000313|EMBL:KYO65170.1,
RC ECO:0000313|Proteomes:UP000075737};
RA Patel B.K.;
RT "Draft genome of Thermovenabulum gondwanense isolated from a red
RT thermophilic microbial mat colonisisng an outflow channel of a bore well.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO65170.1}.
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DR EMBL; LOHZ01000037; KYO65170.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A162MBM3; -.
DR STRING; 520767.ATZ99_17590; -.
DR PATRIC; fig|520767.4.peg.1874; -.
DR OrthoDB; 9806952at2; -.
DR Proteomes; UP000075737; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000075737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 272..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 476..631
FT /note="HD/PDEase"
FT /evidence="ECO:0000259|SMART:SM00471"
SQ SEQUENCE 707 AA; 78556 MW; 17B076C2E824B8EE CRC64;
MSLDLKRDNR RIIMKIKLLQ NNKAQKVLLG LIFFLSITSL VITNALPKKY DLKVGDVLQE
DIIAEKEAID TIATKKLQEA AAESVPQKYT LDQTVVKEVK AQLTELFENV REIRSKDYLD
IKEKAKILKE NVTLSLSNES YLTFLNMDLV QLKELETITK AVIETVMDSG IKDDSIDRAK
AFVIEEFKKV NLPQNVKSLG MEIAISVIKP NMVLDREATE KGIKMAMEAV EPVKISKGQV
LIEKGKPVTA EQLALLKELG LLAQDNRVNL TIISGISLLV LILELILGYY IYFYFRNYYD
NNIDLLLLTI VIFSTLALSV IFKHISPFLL PLAAGGMLIT VLLNPQIALV SLFIMSIITG
ILMGNEFSYS MMSVLGGIIG ILFTSKISQR PDLTKAGGVV GLVNSLVILC VGLLDHLPWI
EIARNAFWGM LAGILSSILT VGTLPFFENA FGVTTSVRLL ELSNPNQPLL RKLLVEAPGT
YHHSIIVGNL AEAAAEAVGG DSLLARVGAT YHDIGKLKRP YFFIENQFAQ ENPHDKLNPS
LSALIIVSHI KDGLELAKQY KLPRIIMDFI AQHHGTSLLT YFYSKALSQE KTTEEVSFRY
DGPKPQTKEI AIIMLADSVE AAVRSMNKPT PGKIDGLIRQ IIKEKLADGQ LDESNLTLKD
LDKIANAFSK VLTGIFHNRI EYPEKVKELE RKGKYVNGDN KQSAGCN
//
