GenomeNet

Database: UniProt
Entry: A0A162NE90_PHYB8
LinkDB: A0A162NE90_PHYB8
Original site: A0A162NE90_PHYB8 
ID   A0A162NE90_PHYB8        Unreviewed;       352 AA.
AC   A0A162NE90;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   16-JAN-2019, entry version 16.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=PHYBLDRAFT_187125 {ECO:0000313|EMBL:OAD73508.1};
OS   Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 /
OS   NBRC 33097 / NRRL 1555).
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Phycomycetaceae; Phycomyces.
OX   NCBI_TaxID=763407 {ECO:0000313|EMBL:OAD73508.1, ECO:0000313|Proteomes:UP000077315};
RN   [1] {ECO:0000313|EMBL:OAD73508.1, ECO:0000313|Proteomes:UP000077315}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 1555(-) {ECO:0000313|Proteomes:UP000077315};
RG   DOE Joint Genome Institute;
RA   Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA   Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA   Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA   Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J.,
RA   Gutierrez G., Heitman J., Henrissat B., Iturriaga E.A., Lang B.F.,
RA   Lavin J.L., Lee S., Li W., Lindquist E., Lopez-Garcia S., Luque E.M.,
RA   Marcos A.T., Martin J., Mccluskey K., Medina H.R., Miralles-Duran A.,
RA   Miyazaki A., Munoz-Torres E., Oguiza J.A., Ohm R., Olmedo M.,
RA   Orejas M., Ortiz-Castellanos L., Pisabarro A.G., Rodriguez-Romero J.,
RA   Ruiz-Herrera J., Ruiz-Vazquez R., Sanz C., Schackwitz W., Schmutz J.,
RA   Shahriari M., Shelest E., Silva-Franco F., Soanes D., Syed K.,
RA   Tagua V.G., Talbot N.J., Thon M., De Vries R.P., Wiebenga A.,
RA   Yadav J.S., Braun E.L., Baker S., Garre V., Horwitz B.,
RA   Torres-Martinez S., Idnurm A., Herrera-Estrella A., Gabaldon T.,
RA   Grigoriev I.V.;
RT   "Expansion of signal transduction pathways in fungi by whole-genome
RT   duplication.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; KV440981; OAD73508.1; -; Genomic_DNA.
DR   RefSeq; XP_018291548.1; XM_018439330.1.
DR   GeneID; 29000236; -.
DR   OrthoDB; 1034517at2759; -.
DR   Proteomes; UP000077315; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000077315};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077315};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361}.
FT   DOMAIN       36    337       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   352 AA;  38134 MW;  6640FD1A5325496F CRC64;
     MEDLRVTGYN ALLTPAFLQE ELAPTPESRQ TVSAARQETA AILRGEDDRL VIIVGPCSIH
     DTKAAKEYCQ RLSKVRENVK GELLIIMRSY FEKPRTTVGW KGLINDPDIN NSYNINKGLR
     VGRELLCELT NSGMPVAVEL LDTISPQYLA DLMSWGAIGA RTTESQLHRE LASGVSFPVG
     FKNGTDGNVR VAIDGIGSAS APHHFLGVTK SGTVSITHTT GNPDCHVILR GGNDGPNFDK
     EHILAAKQAM IKAGLRPNIM VDCSHGNSNK DHRNQPKVAD NICEQIASGE TSVIGLMIES
     HINEGKQSVP AEGPQALKYG VSITDACIDF ETTEQVLTNL ANAVKARRSL KQ
//
DBGET integrated database retrieval system