ID A0A162PUM7_PHYB8 Unreviewed; 615 AA.
AC A0A162PUM7;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Protein phosphatase PP2A regulatory subunit A {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHYBLDRAFT_154899 {ECO:0000313|EMBL:OAD76137.1};
OS Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC
OS 33097 / NRRL 1555).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Phycomycetaceae; Phycomyces.
OX NCBI_TaxID=763407 {ECO:0000313|EMBL:OAD76137.1, ECO:0000313|Proteomes:UP000077315};
RN [1] {ECO:0000313|Proteomes:UP000077315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1555(-) {ECO:0000313|Proteomes:UP000077315};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA McCluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the phosphatase 2A regulatory subunit A family.
CC {ECO:0000256|ARBA:ARBA00038332}.
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DR EMBL; KV440976; OAD76137.1; -; Genomic_DNA.
DR RefSeq; XP_018294177.1; XM_018433362.1.
DR AlphaFoldDB; A0A162PUM7; -.
DR STRING; 763407.A0A162PUM7; -.
DR GeneID; 28994268; -.
DR VEuPathDB; FungiDB:PHYBL_154899; -.
DR InParanoid; A0A162PUM7; -.
DR OrthoDB; 759105at2759; -.
DR Proteomes; UP000077315; Unassembled WGS sequence.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR021133; HEAT_type_2.
DR PANTHER; PTHR10648:SF4; PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED; 1.
DR PANTHER; PTHR10648; SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT; 1.
DR Pfam; PF02985; HEAT; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 10.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000077315};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 34..72
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 73..110
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 188..226
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 227..265
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 266..304
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 344..382
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 383..421
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 422..460
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 500..538
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 539..577
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 615 AA; 68701 MW; 9247794C5F2595AA CRC64;
MTGLGLRSMS PGTPGSLPSS EDTNRENEEQ ELYPIAVLVD ELKNEDVQLR LNAIRNLGTI
AMALGPQRTR DELIPFLNDS IDDEDEVLLA VADELSKFSE YVGGPEYAHF MLGPLENLSA
VEEVLVRDKA VESLCKIVAL LNSSQIEHYF MPLLKRLTSG EWFTSRISAT GLYAAGYSKC
TPEQRSELKV LFAQLIQDDT PMVRRAAAKS LKDLIKELSK DVIISNILPL FIKLSSDDQD
TVRLLTVEDL VQMARILSPE ESKQHLLPIL KQLGQDKSWR VRYMVATHFT EICEVLGETI
TREELVTLFV SLIKDSEGEV KMTTIGQAPA FAKKVDETTV VNKILPCIKD LVIDTNQHVR
AVVAINISGL APIVGKDLTI EYLLPLFLQL LKDDFPEVRL NIISKLEHVN QVIGVERLSQ
SLLPAIVELA EDKQWRVRLA IIEYIPLLAK QLGVGFFDEK LLSLCMSWLC DTVFSIREAA
TTNLKQLVDI FGCEWATETV LPQVMDMATN TNFLFRMTSL FALGTMATSL SPEIIQDKVL
PTVLELKTDP IPNIRFNVAK SLEVLTPILR QSPATADLVN THVAPALQDL SNDNDVDVRW
FAERAILTAT KLTVY
//
