ID A0A162R6H6_MUCCL Unreviewed; 1149 AA.
AC A0A162R6H6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Homeodomain-like DNA binding domain-containing transcription factor {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=MUCCIDRAFT_136222 {ECO:0000313|EMBL:OAD08780.1};
OS Mucor lusitanicus CBS 277.49.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=747725 {ECO:0000313|EMBL:OAD08780.1, ECO:0000313|Proteomes:UP000077051};
RN [1] {ECO:0000313|EMBL:OAD08780.1, ECO:0000313|Proteomes:UP000077051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 277.49 {ECO:0000313|EMBL:OAD08780.1,
RC ECO:0000313|Proteomes:UP000077051};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA Mccluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De Vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAD08780.1}.
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DR EMBL; AMYB01000001; OAD08780.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A162R6H6; -.
DR STRING; 747725.A0A162R6H6; -.
DR VEuPathDB; FungiDB:QYA_136222; -.
DR OrthoDB; 5482994at2759; -.
DR Proteomes; UP000077051; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0042393; F:histone binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd17996; DEXHc_SMARCA2_SMARCA4; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR014978; Gln-Leu-Gln_QLQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014012; HSA_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029295; SnAC.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR10799:SF973; ATP-DEPENDENT HELICASE BRM; 1.
DR PANTHER; PTHR10799; SNF2/RAD54 HELICASE FAMILY; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07529; HSA; 1.
DR Pfam; PF08880; QLQ; 1.
DR Pfam; PF14619; SnAC; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00951; QLQ; 1.
DR SMART; SM01314; SnAC; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51204; HSA; 1.
DR PROSITE; PS51666; QLQ; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000077051}.
FT DOMAIN 1..35
FT /note="QLQ"
FT /evidence="ECO:0000259|PROSITE:PS51666"
FT DOMAIN 198..279
FT /note="HSA"
FT /evidence="ECO:0000259|PROSITE:PS51204"
FT DOMAIN 377..542
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 685..874
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1024..1094
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 57..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 959..991
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1114..1149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 968..991
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1132..1149
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OAD08780.1"
SQ SEQUENCE 1149 AA; 133614 MW; 16F6993C0604D6C5 CRC64;
FLPHQLNALK NQIIAYKLLI KNAPLPPRLQ QAVLAPSNSL LAQSSPPMTP IVTPKVIHQQ
PHQERPQSVP PTPPTPQHQE FDAYLPPTAL LANPITSYAH ASRHQRILIP SLLPAGIDPQ
AIRSDREKRM LARMTHQYQQ PATHVQEHIR SKALKLYQKQ SQLRKEFVQG VEKSTVLATS
AHHTMFKRTK RVSRLDSQQV EAVEQVQRRQ QEAYIQEAKH NRLHALYQHG SALSHESKLK
RNTLTQLGRA VLHYHQSVAK AEQKKMERIA KERMQALKNN DEEAYLRLLD QAKDTRLTDL
LRQTDLFLQS LTASVVEQQQ STGIPHQEHL KQQQQHEVSS ADYFRITHKI HEDVSQPAIM
VGGQLKQYQV RGLQWMISLY NNNLNGILAD EMGLGKTIQT ISLITYLIEK KQQNGPFLII
VPLSTLPNWT MEFDKWAPSV SKIVYTGPSH QRKELASMVR SGQFQVLLTT FEYIIRDTQA
LCRTKWLYLI MDEGHRMKNA NAKLTVTLRQ KFHARYRLIL TGTPLQNNLP ELWALLNFIL
PKIFKSVKTF EEWFNTPFSN QGAHDKVDLN EEEQLLIIKR LHKVLRPFLL RRLKSDVESE
LPDKVEKVIK CKLSSLQVKL YHQLKNTHVN SNGYFPIAYK KLNNTIMQLR KVCNHPFIFE
GVENALNPKG KANELLYRCS GKLELLDRML PKLQRTGHRV LIFFQMTGIM NIMEDYLNWR
HYRYLRLDGN TRSEDRSTLL HHFNQPDSPY FIFLLSTRAG GLGLNLQSAD TVILFDSDWN
PHQDLQAQDR AHRIGQTKEV RIFRLVTSNS IEERILATAQ YKLGIDGKVI QAGKFDNRST
EADREALLRT LLEDKMQEEA WDEDASNQEL NNVLKRSDQE LSVFEMMDSE RRSHPSQQGE
RLIQENELPD VFDIKDHVAV DLSPVMPDTD RSRKAKQNIK YDDGLTDAQF MRAIQEGQLM
PPRIENKRPL LSTDKSSRKR SKVEPEKTPE VDTVSRLMRK QLTEIFEACY KEVEKSIAVE
DDGYYRKRCE LFMDLVDKRD YPDYYTLIKN PISMNMIKQR MHSFYYEDIH EFKNDFAVMF
ENARIFNEEG SAVYEDANEM EKILNDELEK QCPRGVLPPY RKRKTAIEQD FVEDPFDGDD
HDEDQEDDE
//
