ID A0A162RMA3_9BACL Unreviewed; 599 AA.
AC A0A162RMA3;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Penicillin-binding protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PNBC_14125 {ECO:0000313|EMBL:OAB73227.1};
OS Paenibacillus crassostreae.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1763538 {ECO:0000313|EMBL:OAB73227.1, ECO:0000313|Proteomes:UP000077134};
RN [1] {ECO:0000313|EMBL:OAB73227.1, ECO:0000313|Proteomes:UP000077134}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LPB0068 {ECO:0000313|EMBL:OAB73227.1,
RC ECO:0000313|Proteomes:UP000077134};
RA Shin S.-K., Yi H.;
RT "Paenibacillus sp. LPB0068, isolated from Crassostrea gigas.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAB73227.1}.
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DR EMBL; LSFN01000025; OAB73227.1; -; Genomic_DNA.
DR RefSeq; WP_068659202.1; NZ_LSFN01000025.1.
DR AlphaFoldDB; A0A162RMA3; -.
DR STRING; 1763538.LPB68_06165; -.
DR KEGG; pcx:LPB68_06165; -.
DR OrthoDB; 2985542at2; -.
DR Proteomes; UP000077134; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000077134};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..229
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 271..585
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 599 AA; 65779 MW; B8B51991CDEEE5B7 CRC64;
MISQQKKRIF YSLMLITACI AILVFRLAYI QFFMRTMQLP NSNHTLQEMS MLQRERAIVL
DSGRGTITDR HGESLTGETI PAVVLFPINR DSIKREAVDS KITKIAESLG IDIQSFHELW
QNLQEPMFLL KVNEKTPISL TLAQANLITD LNVNGIKVLP YRKRYRGTPS GMQWLGYLSQ
QPKIANSSDL GVIKKYGASG LEKTLEPLLK GVGPTVAYYT VDSRSNVLSD IGVHVKAPNN
SYYPLRLTTT IDKQIQQQIE RLTEQSGMKR GAVVVLDTNN ADIVAMVSAP FYNPMAIDPE
QGEWNNKALQ AAIPGSIFKT VIAAAALEAG VTSPNEEFHC NGHYGRYGLS CWKDGGHGKL
TLEQAYAKSC NVVFATLAER LNSDQITRTA RALGVGRRIG WKDHDVLGYS SLIPLDHEET
GEIFASSTTM DGGVRAQTGI GQRDVTMTPL QAANMVVTLL HGGQVQTPRI LERISYHNGQ
VMQILKPHAY PKTFNSIQPA TAKLLCVWMR RVVTDGTGQA LSRAKWTLAG KSGTAQVILK
GSPKNNQWFI GYGPVEQPKY AVAVLFQNVD PDVNNKATAL FGQIMGVLSS VDGVSATAG
//
