ID A0A162RW16_9CRUS Unreviewed; 1967 AA.
AC A0A162RW16;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Down syndrome cell adhesion molecule 4 {ECO:0000313|EMBL:KZS20828.1};
GN ORFNames=APZ42_012467 {ECO:0000313|EMBL:KZS20828.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS20828.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS20828.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS20828.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS20828.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS20828.1}.
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DR EMBL; LRGB01000115; KZS20828.1; -; Genomic_DNA.
DR STRING; 35525.A0A162RW16; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR CDD; cd00063; FN3; 6.
DR CDD; cd00096; Ig; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 15.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR44170:SF48; MYOPALLADIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 5.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF13927; Ig_3; 4.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 9.
DR SMART; SM00408; IGc2; 8.
DR SMART; SM00406; IGv; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 9.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 8.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 89..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1730..1752
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 205..310
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 323..425
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 431..527
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 532..616
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 621..756
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 758..849
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 860..965
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 972..1064
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1069..1161
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1166..1270
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1274..1374
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1373..1501
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1505..1607
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1617..1707
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 667..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1144..1165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1780..1808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1887..1916
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1932..1955
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..692
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1144..1158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1893..1916
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1967 AA; 213947 MW; 264883BF5BEC9BF7 CRC64;
MMDTFASSGT AAAAGPRFQN QLPSDVTFTP DRGFTIECPV WGQPTPQITW LTSKVKVDYA
KWKSTTDCIF MCVTSLTVDR QMKKYRYSWL LFELKSAAFA YLAIAFLFES TFTKRFIQKW
LPSAWDVSCN GSNGTQFLKV EKVPRKNGRH VMLANGDLHV LSARQGDENH LYHCRVLVQP
NGQTMTSSTA GRIILSQETM TKMAPVIVES VNRIRVWRGQ DAVLPCVFHG YPPPKVKWYK
SQTIQYGNLL LPLVASAATQ EHRGGVLGLG RHRLVGGTLL IASVVAEDQG RYICSVNNSM
GLVESRTELV FRDKLQVRIV ESSNVVVVAA AASAAQHIQV VDAETSVTIT CHFSGSPRPV
VSWLKDGQRY LVGNSGRVSS SSGDDGYTDM VQLSISSVQR EDEGIYQCLA SNDEGDWAQA
SAQLAIGAFP PHLKETFSRQ VLHPGSSVSL KCLASGTPLP HFTWTLDGFP LSPVSERYFL
GQQQQTGHDD LVVAHLNITH VRVEDGGNYK CAAENRVGRV EHSANLHIYG APYVRRMSTV
VGVGGKRLEL PCPVAGYPIE AITWEKATAT TTTSVRLVNE FTATLTIESL TGQHGGWYVC
RAANEGGRAE SAVHVVVQAG PRITPFGMPS RNVMVNSRVQ VSCVIEEGDP PFHIRWYRDD
KPLVHPHHHL SSSSASSPSQ HRPANPVGVA SLSSTDPPIR LGPLGAIANG LRLTDFNSYS
SILTIDQVTV NHGGNYSCRA ENAAGTAVHS TLLHVSVPPF WVNQQPPADT VQTVSGHSVE
LKCHVHGVPT PQVIWSFTRD KTADKYTTLF ANTNRTLLAN QSLVISPVDV SDAGYYQCEA
SNGVGNNINA LMALQVHAPP EVHLNQDYMA VRRGSLTGTV LKCSIRGDPP LNIHWRKDSV
PLDPTQSRVV TRAQPATGSH PSSSLHATLL TSELSVTNAA VADEGLYECA ASNMHGEDSD
AVFLQVQDVP QPPLDVRVAS AAGRRIQLEW KPPAADGGNP LQEFIIFYQS PGGDVRQERI
MASQFSGSIG NLQPATVYQV YMTASNALGQ SQPSLGLTVT TDEEAPEGHP LQVGASSVHA
RGFTLSWAPP AHQLQHGIIQ SYLVTIDSGR MLNRTVLPSS SNEYTMAGLR PNTNYHAYVQ
AVNNQGSGPA SPSVSVKTSE APPEEPPLNV ACVSLNSQSL QITWQPPPAD YRNGLLRGYR
IFYEPLSELL YLSSPDQSDL QTGSSQTTTE LTVFLSGLQK FANYSIQVLA FTGAGDGAKS
QPLTCTTEED IPEMPTRLKI VQSGPDSLTI SWLPHPRPTS RVTHFTVYSK EIERGQDVNP
QKWTAANSGP SAGRLEIRNL RPRRAVFYFQ AAAVSGQAGE GPRSSTVSFT FNPTNKIVAA
VVSIGSGYLV ARGSRLILPC TALGDTPLQI SWLQDGRQLS DWLNLNPLKL GEQIQQPWIQ
QRPHDPDDPD DPDDENATAG LIQVLTNGSL SIGQLSHNGG GNYTCQARNR HGQDQVDYWL
TVVTPPPAPQ LRFAASNWSS VTLQWASGSP STDQSNRTRV SAARHYVIKY RPREAARWAQ
IVLPATWRSV PVGDLNCGTE YEFVLVASSR VGNSSSSNVV TAKTKGSPPE YLAADARHSD
LTLTPTSCTV DLVRWQDRGC PIQQFIFRFR LATDSAGEWI IAGAESPPQQ TFLLAGLIPG
RDYAVRVTAL NAAGSAQRDY SVRTPPLMDS HSKSDVHGGS LAPLFSDPRV AVPMAVSSLA
IVLTIVTLLL RYRYRSGTDY LRPDSHPQTV GNANVRTYAD GGDTPEDGNS STLSACQKRP
PPMDCSGRLS DYAPDQVSPY AVFPSLTSSG GKSQFSSSRR MKTFVVDGSK DSLSVEMSNY
APPAPSMIRR MHQQQAEEEP MYDYIAPCAT ASGPNPSGPN LSGPNPSGRS NKLTSNPQSV
FVPIIPARST WNQQQQMYRQ QHGPNQSSPH YHGDWNNQET LALSQRL
//
