ID A0A162S555_9CLOT Unreviewed; 800 AA.
AC A0A162S555;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon {ECO:0000313|EMBL:KZL90784.1};
GN ORFNames=CLMAG_36950 {ECO:0000313|EMBL:KZL90784.1};
OS Clostridium magnum DSM 2767.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121326 {ECO:0000313|EMBL:KZL90784.1, ECO:0000313|Proteomes:UP000076603};
RN [1] {ECO:0000313|EMBL:KZL90784.1, ECO:0000313|Proteomes:UP000076603}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2767 {ECO:0000313|EMBL:KZL90784.1,
RC ECO:0000313|Proteomes:UP000076603};
RA Poehlein A., Uhlig R., Fischer R., Bahl H., Daniel R.;
RT "Genome sequence of Clostridium magnum DSM 2767.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC {ECO:0000256|ARBA:ARBA00038058}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZL90784.1}.
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DR EMBL; LWAE01000004; KZL90784.1; -; Genomic_DNA.
DR RefSeq; WP_066625550.1; NZ_LWAE01000004.1.
DR AlphaFoldDB; A0A162S555; -.
DR STRING; 1121326.CLMAG_36950; -.
DR PATRIC; fig|1121326.3.peg.3739; -.
DR Proteomes; UP000076603; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 1.10.275.40; -; 1.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 1.10.30.20; Bacterial XPD DNA helicase, FeS cluster domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006554; Helicase-like_DEXD_c2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR InterPro; IPR042493; XPD_DNA_FeS.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00488; DEXDc2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KZL90784.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000076603}.
FT DOMAIN 201..462
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
SQ SEQUENCE 800 AA; 93409 MW; A14283527A7DFFAC CRC64;
MENNKIKISV RNLVEFVLKS GDLDSRFTGT SRAMEGTKAH QKIQKEYKNK FSKEKQIPLE
EFEANKKIEY MAEVILKYDI EYKNFHFIIE GRADGIIVEG LDITIDEIKS LTKPLELVDE
EYNYLHWAQA KCYGYIYAIQ NNLEDINVQI TYYNINSEET KSLRKNFNVK ELEIFFFSLL
DGYYFWASFM KDWKIKRNFS IKKMSFPFKC YRKGQRELAV AVYGTIKEGR KIFAQASTGI
GKTMSTLFPS IKAMGEGFVS KIFYLTAKTI TRNVAEDAII KMASGGLSLK VVILTAKDKI
CFKEKTSCNP EDCEFAKGHF DRVNNAISEI LNKENIINRE VVVKYSKQFS ICPFEFSLDL
ALWADCIICD YNYVFDPRVY LRRFFDNEEE YTFLIDEAHN LVDRAREMFS AELDKQPFLE
VKKIMKSKEP KIAKALDKIN SCMIKFRKLC EEQEHNVYIQ KSQMEEVYPL LRRLISESEE
WLTKNNKLEG YEQLLEIYFN SLAFIRISEL YDDRFITYVE KQGSNVRIKI FCLDPSYLLN
ESMKRGKSVV LFSATLSPIG YFKEILGGSD SDYIIRLPSP FSLEKRKLLI ADRVSTKYKD
RESSLTSIIE YIAAMISAKK GNYIVFLPSY SYMTKIYEKF CEEYPLINTM IQESNMIEEN
REKYLFNFKE DNKETLVAFA VLGGMFSEGI DLKGDRLIGA IIVGVGLPQL CLERDIIKDY
FKEKNNFGYE YAYMYPGMNK VLQAAGRVIR TEDDRGSILL IDERFGNSAY KMIFPKEWYS
NITVRSVKDI QNNLAEFWRK
//
