ID A0A162T0U6_9CRUS Unreviewed; 1040 AA.
AC A0A162T0U6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN ORFNames=APZ42_011805 {ECO:0000313|EMBL:KZS21797.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS21797.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS21797.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS21797.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS21797.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS21797.1}.
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DR EMBL; LRGB01000024; KZS21797.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A162T0U6; -.
DR STRING; 35525.A0A162T0U6; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR GO; GO:0048666; P:neuron development; IEA:UniProt.
DR CDD; cd00047; PTPc; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR008356; Tyr_Pase_KIM-con.
DR PANTHER; PTHR46198; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR PANTHER; PTHR46198:SF4; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..1040
FT /note="protein-tyrosine-phosphatase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007839627"
FT TRANSMEM 679..702
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 804..1040
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 958..1033
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 84..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 173..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 567..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..203
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1040 AA; 112354 MW; 89595C005D11ABA9 CRC64;
MKTTVVMRTE LIVGLVGLVC WMTAASQEIQ PDEITTEWIT TDAPVTLVPA LEATAVRSVD
KEITALPPND LRARILLNSD FEDDPTQLTA SQTGGQSAGS TLDNSLRSSN NNDWTPIVWA
STRLVSPPLQ SNFPQSTPFP SPVSVRPPPP GPSTLVIRPT PLLRPLPTIL ATQSRTTTTS
TERTISSSIR LPSTETPTAT LPPVSSRPAV IRFDLDDASS GPTFTIIADP EANDSVIASS
VPVPSEITSI ASIPVPSEIP SMASIPVVSE VTSVGSIPVP SAMPVTVPPI APVPATEQVP
SEIPDSGRVS VTSEIPATGF VPLLVNQTEQ PNDNPLLVDN SSLVVPIVNS EDVANNTAKE
LTGQLDVAEE SFNATENSFA MVANETFPII NETSTAIPVD MNSTDIEVEE NVVLTPSSED
ATGVANTSLI TQPSNVLVAG SEETSQLEDV LTTPIEESPV TTDLSTIFSS NNQSSPTIDV
PSNSSAIDEA NVTVLSTTEN NVPSTSLRAA LVAVSTSDPV TTVTWQPEES TDQERNIGNG
KGNREESGRS TTLSALSGLA TLFPALTRPP STTVLPTETS KPITTSAPLT TPKTTTTSAV
VFTSSGWSVS PQQAPPTPSV PHNVNPLAGW PTTPNPPVTF QEPSVPFYDP TSTEYYPYDE
WPRTEGSETD DQGSTTTTIV AVSVSIAAIL CLAIAILLLL VLRRRRARAV QGTCQPARMD
AYSLDNVSQS NTWQRGKVRN SLRASKRSYC NQAFDDSTVF SVPLTAAQLA LYMEKPITSI
EAEFRNIATS TVRIDELPVG VETKNRYANV LPVPETRVHI RVQENQPADT IEQYINANYI
KGPKEEPHFY IGCQGPMEET VQDFWQMIWE NQCKIIIQLT DLSENGVSRC AEYLPPSEVL
DCHRLYGDYQ VTLKSRELRD NYVTSHIQLK RMEDNLVRDI THLWYSSWPA TGVPEDGKTI
VSLLLEARKG QSKEQRAPMV VHCSPGTGRT GAVLAIDVCM RHLDSSRSID IPRSVHRLRQ
DRAGCVQTGE QYAFIYKVSS
//
