ID A0A162TXK6_PHYB8 Unreviewed; 1146 AA.
AC A0A162TXK6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=IPT/TIG domain-containing protein {ECO:0000259|SMART:SM00429};
GN ORFNames=PHYBLDRAFT_187967 {ECO:0000313|EMBL:OAD70633.1};
OS Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC
OS 33097 / NRRL 1555).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Phycomycetaceae; Phycomyces.
OX NCBI_TaxID=763407 {ECO:0000313|EMBL:OAD70633.1, ECO:0000313|Proteomes:UP000077315};
RN [1] {ECO:0000313|Proteomes:UP000077315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1555(-) {ECO:0000313|Proteomes:UP000077315};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA McCluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KV440988; OAD70633.1; -; Genomic_DNA.
DR RefSeq; XP_018288673.1; XM_018439441.1.
DR AlphaFoldDB; A0A162TXK6; -.
DR STRING; 763407.A0A162TXK6; -.
DR GeneID; 29000347; -.
DR VEuPathDB; FungiDB:PHYBL_187967; -.
DR InParanoid; A0A162TXK6; -.
DR OrthoDB; 2901153at2759; -.
DR Proteomes; UP000077315; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00102; IPT; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR PANTHER; PTHR24148; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED; 1.
DR PANTHER; PTHR24148:SF77; IPT_TIG DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000077315};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1103..1123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 547..632
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|SMART:SM00429"
FT REPEAT 727..759
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 760..784
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 65..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 669..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1146 AA; 127855 MW; EBB0796F6E83F0B7 CRC64;
MQNVSPLLDM ILPTDDASCD SPSGSSTSEP HDEAMNNSQP FIDQSFFYKL DQLSPDNPLF
FMQQSENRPR QSEELDTPMD APSPLSAQAS VSMSSPQSMS TQGFMSAPSS IVEPLQPANS
LPAESSQTFW SGFNNPCVSM ITTVTPQLIV FLFLANYSPD QSSQPSPPPH AVSPIKYEPS
LDTPFSQSPI TRPLDMMKTP GMQIRVLGVP QTGAKSRVET QIKLCIQLVT DDGDKAQWWS
HLKLPEHMVA KDKLKRQVMM ANAQNGLKVD GANLPIKPER MLFLSARVIC ASDPSRKVVT
CLGCIQRERK RSQRRKENKI KTDNEDDNRS MEDDKSLALE EQKVLLFNCS EIVDFSSGDT
ILPTRITCYC RHHNERLGFC IYFEMHDQTG KQVATGMSPP IMITDDHKSN KIKAGRKRPR
TDVESHTPLI SSGGYEMNSG VTAPNMLGPP RFRVPYGSYP NVQTLREQQF SLQPRPVDHV
GMNHDVNHLA NPNSNTMHRQ QFDASSGPKI QPNSIVPSMA TQTHPTPMVT ENTVQQTVTP
TPILNDRPQL QRLIPNEGPT YGGIEVTILG SGFRPGLTCL FGDAAASSTH YWSPNTLVCI
LPPAVEPGTV VVSFKEYPMV MDSQDVTLFT YFNENDRALM ELALQVVGLK MTGKVEDARA
IAMRIVQGGN QNQQSSSGTS NQDNQQNQNQ NQNQNQTCLE RHIIQVLEVM DIMEDVDSVD
VSLTSGQGHT MLHLAAILNF SKLTRTLIEL GCNVDTMDRN GNTALHYAAM FGHEDLAKIL
LDDGKADSGI VNQWNKRPMH LSKDNTMRLI LHTYMPVDAD EVSDSCGASV SSDMLGADVD
TSFSDESSYD DDVISLDGDR VDRNEINQRW LQFYQSDSSA SAQSELYEEG LRNRRRPTLN
IQSIQYLEDD GDLHSPDEIM DAEAVHNNHI DTSSDTDDDG DMSKADLKST WMQRTLSHLQ
QEKDKHLSYV TDNTFVQNIK NNMPAKPTEL NLKTIADHVL QFPRPTEMIA NMSVMFSQDQ
AKGSSTDEPE QTLAWYMALA YSIGAGSRSL PEQPIRPLDQ KQPEMWQFDN KIANASSAQP
SRPQPSSMGP EAIADQKRRD RRLFSLWVPL LCFAVIWLIF QFVSSHPGVI DFVVGISGFR
HQYLRI
//
