ID A0A162V5C3_PHYB8 Unreviewed; 471 AA.
AC A0A162V5C3;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Citrate synthase {ECO:0000256|RuleBase:RU000441};
GN Name=PbCsa {ECO:0000313|EMBL:OAD80102.1};
GN ORFNames=PHYBLDRAFT_74310 {ECO:0000313|EMBL:OAD80102.1};
OS Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC
OS 33097 / NRRL 1555).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Phycomycetaceae; Phycomyces.
OX NCBI_TaxID=763407 {ECO:0000313|EMBL:OAD80102.1, ECO:0000313|Proteomes:UP000077315};
RN [1] {ECO:0000313|Proteomes:UP000077315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1555(-) {ECO:0000313|Proteomes:UP000077315};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA McCluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|RuleBase:RU000441}.
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DR EMBL; KV440972; OAD80102.1; -; Genomic_DNA.
DR RefSeq; XP_018298142.1; XM_018443009.1.
DR AlphaFoldDB; A0A162V5C3; -.
DR STRING; 763407.A0A162V5C3; -.
DR GeneID; 29003915; -.
DR VEuPathDB; FungiDB:PHYBL_74310; -.
DR InParanoid; A0A162V5C3; -.
DR OrthoDB; 3513214at2759; -.
DR Proteomes; UP000077315; Unassembled WGS sequence.
DR GO; GO:0004108; F:citrate (Si)-synthase activity; IEA:InterPro.
DR GO; GO:0006101; P:citrate metabolic process; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR CDD; cd06105; ScCit1-2_like; 1.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR010109; Citrate_synthase_euk.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR NCBIfam; TIGR01793; cit_synth_euk; 1.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF8; CITRATE SYNTHASE, MITOCHONDRIAL; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000077315};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU000441}.
FT ACT_SITE 308
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
FT ACT_SITE 354
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
FT ACT_SITE 409
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
SQ SEQUENCE 471 AA; 52102 MW; 8E1DD193F020AA0F CRC64;
MSSVRAFASL SKAARPAAFR FAPAAAIGAT RTYASKAQTL KERLAELIPQ KQEEVKAFKK
EYGNKVLGEV TVDQAYGGMR GIKGLVWEGS VLDAEEGIRF RGLTIPECQQ VLPAAEGGAE
PLPESLFWLL VTGEVPTAEQ VKGLSAEWAA RSDLPEFVEE IIDRCPKTLH PMSQFSVAVN
ALQHDSQFAK AYSQGIHKSK YWDTTFEDTM DLIAKLPKVA ARIYRNVYAD GKMASIDADK
DYSYNFSKLL GFEGNKDFVE LMRLYLTIHS DHEGGNVSAH TTHLVGSALS DPYLSFAAGL
NGLAGPLHGL ANQEVLRWTL NLKEAVGVDA SEEEIKKYLW KTLNGGQVVP GYGHAVLRKT
DPRYTAQREF ALKHLPDDPL FGLVSKLYHI IPGVLTEHGK TKNPWPNVDA HSGVLLQYYG
LKEQDYYTVL FGVSRALGVT SQLIWDRALG MPLERPKSYS TAYLKKMFAK N
//
