ID A0A162YRE6_MUCCL Unreviewed; 799 AA.
AC A0A162YRE6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 13-SEP-2023, entry version 30.
DE RecName: Full=AMP deaminase {ECO:0000256|ARBA:ARBA00012775};
DE EC=3.5.4.6 {ECO:0000256|ARBA:ARBA00012775};
GN ORFNames=MUCCIDRAFT_173785 {ECO:0000313|EMBL:OAD00167.1};
OS Mucor lusitanicus CBS 277.49.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=747725 {ECO:0000313|EMBL:OAD00167.1, ECO:0000313|Proteomes:UP000077051};
RN [1] {ECO:0000313|EMBL:OAD00167.1, ECO:0000313|Proteomes:UP000077051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 277.49 {ECO:0000313|EMBL:OAD00167.1,
RC ECO:0000313|Proteomes:UP000077051};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA Mccluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De Vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- PATHWAY: Purine metabolism; IMP biosynthesis via salvage pathway; IMP
CC from AMP: step 1/1. {ECO:0000256|ARBA:ARBA00004955}.
CC -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676,
CC ECO:0000256|PIRNR:PIRNR001251}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAD00167.1}.
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DR EMBL; AMYB01000007; OAD00167.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A162YRE6; -.
DR STRING; 747725.A0A162YRE6; -.
DR VEuPathDB; FungiDB:QYA_173785; -.
DR OrthoDB; 20951at2759; -.
DR UniPathway; UPA00591; UER00663.
DR Proteomes; UP000077051; Unassembled WGS sequence.
DR GO; GO:0003876; F:AMP deaminase activity; IEA:UniProtKB-EC.
DR GO; GO:0032264; P:IMP salvage; IEA:UniProtKB-UniPathway.
DR CDD; cd01319; AMPD; 1.
DR Gene3D; 4.10.800.20; -; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR006650; A/AMP_deam_AS.
DR InterPro; IPR006329; AMPD.
DR InterPro; IPR032466; Metal_Hydrolase.
DR NCBIfam; TIGR01429; AMP_deaminase; 1.
DR PANTHER; PTHR11359; AMP DEAMINASE; 1.
DR PANTHER; PTHR11359:SF0; AMP DEAMINASE; 1.
DR Pfam; PF19326; AMP_deaminase; 1.
DR PIRSF; PIRSF001251; AMP_deaminase_met; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
DR PROSITE; PS00485; A_DEAMINASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000077051}.
FT REGION 140..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 799 AA; 91758 MW; 6F91E001CA832270 CRC64;
MPNTIYSNKK RQADGIDIPS DEGINNFDDS PYFDYHHLKA IENHDSKYLC QSLSVSPAAN
HLSDLHIDDD EALPTLPQVP EKSSFLKEPV THTADPNAKF EAKDDAITAE LCVLYGNLQK
CLDLREKYIT LSSQRLMDDP RNHDDWNIYP APPPKSWPLP SPEELERRKA KEKAREADPV
AAVGSDFDFD QCEIPGPHVY SFGVGPDGFY QVYKNELDQT AGHPLHPVPS PREFYDDMEF
ILSVISDGPA KSFAFRRLRY LDSKWQMYIL LNEFQELADS KRTPHRDFYN VRKVDTHVHH
SSSMNQKHLL RFIKSKMKKS PDDVVIYRDN HHLTLRGVFE SLGLTAYDLS IDTLDMHAHK
DSFHRFDKFN LKYNPIGESR LREIFMKTDN YIQGKYLAEI TKEVVSDLES SKYQMVEYRV
SIYGRSIDEW DKLAKWVVNN KLFSANVRWL IQIPRLYNIY KASNAINSFQ DIITNVFEPL
FEVTKDPSSH PELHVFLQRV IGFDTVDDES KPEKPIFKDF PLPKDWTSGV NPPYSYYLYY
MYANTAALNK WRQARGFTTL VLRPHCGEAG DTDHLTAAFL TSYGISHGIL LRKVPALQYL
YYLAQVGIAM SPLSNNALFL TYERNPLPQF FQRGLNISLS TDDPLQFHFT KEPLIEEYSV
AAQIWKLSST DMCELARNSV IQSGWENQIK THWIGKDWHK PGVEGNDMQK TNVPDIRVGF
RYETLHEELE ALRRYAPKGE SSEHEEPLSK KDYVGVAGLA ESSSIQQHLM SKSPVDKSHI
GSFPGAGLVA ERAKLRSGH
//
