ID A0A163AR04_PHYB8 Unreviewed; 1639 AA.
AC A0A163AR04;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Sec63-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHYBLDRAFT_133151 {ECO:0000313|EMBL:OAD75181.1};
OS Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC
OS 33097 / NRRL 1555).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Phycomycetaceae; Phycomyces.
OX NCBI_TaxID=763407 {ECO:0000313|EMBL:OAD75181.1, ECO:0000313|Proteomes:UP000077315};
RN [1] {ECO:0000313|Proteomes:UP000077315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1555(-) {ECO:0000313|Proteomes:UP000077315};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA McCluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KV440978; OAD75181.1; -; Genomic_DNA.
DR RefSeq; XP_018293221.1; XM_018429551.1.
DR STRING; 763407.A0A163AR04; -.
DR GeneID; 28990457; -.
DR VEuPathDB; FungiDB:PHYBL_133151; -.
DR InParanoid; A0A163AR04; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000077315; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:UniProt.
DR CDD; cd18021; DEXHc_Brr2_2; 1.
DR CDD; cd18795; SF2_C_Ski2; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 2.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF4; U5 SMALL NUCLEAR RIBONUCLEOPROTEIN HELICASE; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02889; Sec63; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 2.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000077315}.
FT DOMAIN 1..161
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 196..409
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 828..1004
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
SQ SEQUENCE 1639 AA; 187313 MW; 10ABA5E2A219E312 CRC64;
MLTILHEIGK NRDPETGLID LDSFKIVYIA PMKALVAEMV GNFSKRLRPY GVQVAELTGD
RQLTKQQIAE TQIIVTTPEK WDVITRKATD RSYTTLVRLI IIDEIHLLHD DRGPVLESIV
SRTIRNMEQT QELVRLVGLS ATLPNYADVA AFLRVDAKSG LFFFDSTFRP CPLKQQFIGV
TEKKAIKRFQ VMNEVCYEKV IEQIEQREEN QVLVFVHSRK ETAKTAKTLR DLALEKDTIG
RFLKQDSASR EILQSEAATV KDANLQDLLP YGFAIHHAGM TRADRTLVEE LFADGHIKVL
CSTATLAWGV NLPAHAVIIK GTQIYSPEKG RWVELSPQDV LQMLGRAGRP QFDTYGEGII
ITAHAELQYY LSLLNTQLPI ESQFISRLAD NLNAEIVLGT IRNRDEAVQW LGYTYLYVRM
LRNPSLYNVS ADDLSDDPYL EQKRVDLIHS AAAVLDKCNL IKYDKKSGRF QVTELGRIAS
HFYVTHHSMA TYNQHLKPMM SHIELFRVFA LSDEFKYIPV REEEKLELSK LLERVPIPVK
ESLEEPTAKI NVLLQSYISQ LKLDGFALVS DMVYVTQSAG RILRAIFEIC LKRGWAQLTK
KALDLCKMVE KRSWLSMSPL RQFKAMPSDL IKRLERKEFP WERYFDLNPQ ELGELVGQPK
AGRQLHKFIH QFPRLDIQAH VQPVTRSLLK MELTITPDFQ WDEKVHGTAE AFWILVEDVD
GETILHHDYF ILKQRYATED HLVSFTVPLY EPLPPNYFVT VVADRWLHAE TKLPVSFKHL
ILPEKYAPHT ELHDLQPLPV SALRNPAYEN VYSRWIKQFN PIQTQAFNAL YTTDDNAFIG
APTGSGKTVC AEFAILRMWN QQSKGRCVYV APFQEIVDQR VVDWQEKFGK LDGGKEIVAL
TGETSADLKL LERGDIIACT PTQWDIVSRR WKQRKNVQNV NLFIADELHL IGGDIGPTYE
VIVSRMRYIA SQTQKTIRIV ALSTSLANAK DLGEWIGAPS QAIFNFHPSV RPVPLEIHIQ
SYNIPHFASL MMAMAKPTYL AITTHSAEKP VIVFVPSRKQ CRLTAVDIIT YCIGDDTPDR
FLHCKIEEIK PFLDRVQDKN LAETLEHGIG FYHEALSKQD KLIVEQLYTN KAIQVVVASR
DTCWGLPLNS HMVIVMGTQY FEGKDHRYAD YPITDVLQMM GRACRPREDD TGKCVLMCQA
NKKEFYKKFL YEALPVESHL DQFIHDHFNA EIVTKTIENK QDAVDYLTWT FLYRRMAHNP
NYYGLQGTSH RHLSDHLSEL VENTLNELQE TKCITVEDEM DVSPLNLGMI AAYYNINYGT
IDMFSVSLKS ATKLKGLLEI VSAATEFEGI PIRHHEDAVL KRLYERLPVK LTSPDFNAPR
FKTNILLQAH FSRMQLPPDL QSDQAMVLGR IIPLLQACVD VISSNGWLSP ALASMELSQM
SVQAMWDRDS PLKQVPYFTN EVIKRCEANQ VESVFDIMEL EDDVRNDVLR MDPSKLREVA
RFVNRYPNIE LGFDVGDADS ISSGNVVNVK VQLERESEDN EEIGPVVAPF FPQKKDEGWW
IVIGDPEQKV LLAIKRVTLQ QKLTVKLDFI APKAGHHNLK VYLMSDSYNG CDQELDMELD
VAEGEDSDEE MSEEESDAE
//
