ID A0A163EFW6_PHYB8 Unreviewed; 1305 AA.
AC A0A163EFW6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=C2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHYBLDRAFT_69648 {ECO:0000313|EMBL:OAD78410.1};
OS Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC
OS 33097 / NRRL 1555).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Phycomycetaceae; Phycomyces.
OX NCBI_TaxID=763407 {ECO:0000313|EMBL:OAD78410.1, ECO:0000313|Proteomes:UP000077315};
RN [1] {ECO:0000313|Proteomes:UP000077315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1555(-) {ECO:0000313|Proteomes:UP000077315};
RG DOE Joint Genome Institute;
RA Corrochano L.M., Kuo A., Marcet-Houben M., Polaino S., Salamov A.,
RA Villalobos J.M., Alvarez M.I., Avalos J., Benito E.P., Benoit I.,
RA Burger G., Camino L.P., Canovas D., Cerda-Olmedo E., Cheng J.-F.,
RA Dominguez A., Elias M., Eslava A.P., Glaser F., Grimwood J., Gutierrez G.,
RA Heitman J., Henrissat B., Iturriaga E.A., Lang B.F., Lavin J.L., Lee S.,
RA Li W., Lindquist E., Lopez-Garcia S., Luque E.M., Marcos A.T., Martin J.,
RA McCluskey K., Medina H.R., Miralles-Duran A., Miyazaki A., Munoz-Torres E.,
RA Oguiza J.A., Ohm R., Olmedo M., Orejas M., Ortiz-Castellanos L.,
RA Pisabarro A.G., Rodriguez-Romero J., Ruiz-Herrera J., Ruiz-Vazquez R.,
RA Sanz C., Schackwitz W., Schmutz J., Shahriari M., Shelest E.,
RA Silva-Franco F., Soanes D., Syed K., Tagua V.G., Talbot N.J., Thon M.,
RA De vries R.P., Wiebenga A., Yadav J.S., Braun E.L., Baker S., Garre V.,
RA Horwitz B., Torres-Martinez S., Idnurm A., Herrera-Estrella A.,
RA Gabaldon T., Grigoriev I.V.;
RT "Expansion of signal transduction pathways in fungi by whole-genome
RT duplication.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KV440973; OAD78410.1; -; Genomic_DNA.
DR RefSeq; XP_018296450.1; XM_018442138.1.
DR STRING; 763407.A0A163EFW6; -.
DR GeneID; 29003044; -.
DR VEuPathDB; FungiDB:PHYBL_69648; -.
DR InParanoid; A0A163EFW6; -.
DR OrthoDB; 1984726at2759; -.
DR Proteomes; UP000077315; Unassembled WGS sequence.
DR Gene3D; 1.10.357.50; -; 1.
DR Gene3D; 1.20.58.1100; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR010439; MUN_dom.
DR InterPro; IPR014770; Munc13_1.
DR InterPro; IPR014772; Munc13_dom-2.
DR PANTHER; PTHR47263; ADENYLATE CYCLASE ACTIVATION PROTEIN GIT1; 1.
DR PANTHER; PTHR47263:SF1; C2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02350); 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF06292; MUN; 1.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS51258; MHD1; 1.
DR PROSITE; PS51259; MHD2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000077315}.
FT DOMAIN 640..759
FT /note="MHD1"
FT /evidence="ECO:0000259|PROSITE:PS51258"
FT DOMAIN 840..955
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 1046..1164
FT /note="MHD2"
FT /evidence="ECO:0000259|PROSITE:PS51259"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 205..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1175..1209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1237..1305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1175..1189
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1241..1280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1305 AA; 148705 MW; 7D84E5446A6815AE CRC64;
MEIKSTSTLR RGGGGAKRAT RTLNPTQVYD YALRCAIRAC IEQSGPQPVV KEPKKERQSV
HIGVGDVFGS ITDKFGEESK PDKLTKEIVR GLMRRVDDIS KAKDTSKAEY QDKRFLTVIS
QFQKVLLQHR YKPTGTVNDL VIIFLKTSEV ELKRANPNPA IWYEELNRYI AIFAELVIQT
VQEDAPSAAT PELMEKLNGF VGPSKSAAAA GGGGENGKSG AGASGGRRAP EKKPTPGAPS
SPLPSGSIEA LENFPMVKTV QSLFQMDDAD HRKKLRELQP ICTESALLLD LKKCINNVHT
NQPFPGRRED FPSQQMYDNW QKRELKQLTE LMKTLMLMNP KLSLGAGSET DVGSSNLLAK
GPTRRQGSLT DTNRSSIYNI QEDVPLPSPR TESLQSPFTY VPNDPRSFFR LLMNMCIDYD
TKVTPDAERA KTSVLSQQSD ELLRECWKTW RLTSPYRAVL YLELVKTRFE LGELDFEDIR
DATRALDKAI KENDVNSWAI NDMLYQNIGK LGNPEWVADL VGMLDKIYEN TAYLEDHADP
LQEFILLEET IEGAAVERWR YIEKVSNNPE NDDLTNLLTM ADKLQKELVS LSKRKFKTPI
KGILSIPGIV MSRQMPYFAL EIDNWAFSKE ASTASIDVTF EFYQKVLSLK RLYDQHGPKK
QTSLFKVESW FLQHVRRWLS TTSAATLEWV ENAIKEDHFE SINETAMHSS SIVDLFSMFH
QAVDFVQSLQ WPNDLQHCRF LTALSKVIGV AIEEYTYTLE DMITEDINPR IEHTPEVAAN
TSFLDRARFQ LYGARGTAKD EGVPADFTPE AINDIEAARG RLDRLYQIME VDDIAEIMRE
FGSPSTAVEK TENNNFLYSI KIVRAEDLQP LDKNGLSDPY VVLEINGKQI TRTRTVYETL
NPRWDQIFDI WLTEKAVDVL AVVYDEDMIG ANEECGLVWF KLSPEYFDDY QSHELGLNLH
PQGKLILRVS MEGEKDDIQF WFGKAFRTLK RAENDAAGLI VDRMGRYMRQ CLSRRILDRV
LGRDRSFFSA FNRATKQADI TLQECEDAIA PLLDYLEKNL HVLNDHLSEA NMQMVLLRVW
KEILLTLECV LLPPLSEQPS EMKPLDDYEI HVVFKWLELL KILFNGGEDG DAVPIDRLET
SQYYALLAIN AAYNVDTETL IQDYHTVLKN QVEMKMRGGR KADRSKTVYH SKHTVRRRKT
DRKSVSMDMP SSETILRILR MRPGKHVQSF LHAEFEKRKN PPNAAQQQQQ QQQDQQLQIQ
EQSQEGLPQQ QQQQQFIASG DNADVILPME SGYPGTPSEE TTLPM
//
