ID A0A163IE14_9MICO Unreviewed; 390 AA.
AC A0A163IE14;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=Citrate synthase {ECO:0000256|PIRNR:PIRNR001369};
GN ORFNames=AVW09_07815 {ECO:0000313|EMBL:KZE43011.1};
OS Microbacterium sp. T32.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=1776083 {ECO:0000313|EMBL:KZE43011.1, ECO:0000313|Proteomes:UP000076494};
RN [1] {ECO:0000313|Proteomes:UP000076494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T32 {ECO:0000313|Proteomes:UP000076494};
RA Hong K.W.;
RT "Whole genome sequencing of Bhargavaea cecembensis T14.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+);
CC Xref=Rhea:RHEA:16845, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57288; EC=2.3.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00000308};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC {ECO:0000256|ARBA:ARBA00005163}.
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|PIRNR:PIRNR001369,
CC ECO:0000256|RuleBase:RU003406}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZE43011.1}.
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DR EMBL; LQQP01000002; KZE43011.1; -; Genomic_DNA.
DR RefSeq; WP_063256302.1; NZ_LQQP01000002.1.
DR AlphaFoldDB; A0A163IE14; -.
DR STRING; 1776083.AVW09_07815; -.
DR OrthoDB; 9800864at2; -.
DR UniPathway; UPA00223; -.
DR Proteomes; UP000076494; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0036440; F:citrate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR011278; 2-MeCitrate/Citrate_synth_II.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR024176; Citrate_synthase_bac-typ.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR NCBIfam; TIGR01800; cit_synth_II; 1.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF4; CITRATE SYNTHASE, PEROXISOMAL; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PIRSF; PIRSF001369; Citrate_synth; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000076494};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR001369}.
FT ACT_SITE 263
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
FT ACT_SITE 314
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
SQ SEQUENCE 390 AA; 42391 MW; D3A6542BAA33A84D CRC64;
MTDVEIKKGL AGVTVDYTAV SKVNPETNSL LYRGYPVQEL AATQSFEAVA LLLWNGELPT
TKELREFEAF ERSHRALDDA VRTTIDLLPL DAHPMDVVRT AVSVVGALAP AAEVADNSAA
SDLAKAKLLF AKIPAIVAYD QRRRRGEAIV EPRADLDYSR NFLWMTFGEE ADEVVARAFA
VSMVLYAEHS FNASTFTARV ITSTTADLYS AVVGAIGALK GALHGGANEA VMHIFDEIGS
AENVGPWLDT ALAEKRKIMG FGHRVYKKGD SRVPTMKAAL DTLVEHYDAH DLASLYDALE
AEFVGRKGIY PNLDYPSGPA YHLIGFDTPT FTPLFVSARI TGWTAHVIEQ AASNALIRPL
SAYAGVDERH IEGYVATEAE REVAERAAEA
//
