ID A0A163JYC9_ABSGL Unreviewed; 426 AA.
AC A0A163JYC9;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Nickel/cobalt efflux system {ECO:0000256|RuleBase:RU362101};
GN Name=ABSGL_11301.1 scaffold 12295 {ECO:0000313|EMBL:SAM05426.1};
OS Absidia glauca (Pin mould).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Cunninghamellaceae; Absidia.
OX NCBI_TaxID=4829 {ECO:0000313|EMBL:SAM05426.1};
RN [1] {ECO:0000313|EMBL:SAM05426.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101.48 {ECO:0000313|EMBL:SAM05426.1};
RA Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA Babar A., Rosenke K.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362101};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362101}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NiCoT transporter (TC 2.A.52) family.
CC {ECO:0000256|ARBA:ARBA00010892, ECO:0000256|RuleBase:RU362101}.
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DR EMBL; LT554468; SAM05426.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A163JYC9; -.
DR STRING; 4829.A0A163JYC9; -.
DR InParanoid; A0A163JYC9; -.
DR OrthoDB; 2725900at2759; -.
DR Proteomes; UP000078561; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015099; F:nickel cation transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR004688; Ni/Co_transpt.
DR InterPro; IPR011541; Ni/Co_transpt_high_affinity.
DR NCBIfam; TIGR00802; nico; 1.
DR PANTHER; PTHR31611; HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1; 1.
DR PANTHER; PTHR31611:SF0; HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1; 1.
DR Pfam; PF03824; NicO; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362101};
KW Nickel {ECO:0000256|ARBA:ARBA00022596};
KW Reference proteome {ECO:0000313|Proteomes:UP000078561};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362101};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362101};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362101}.
FT TRANSMEM 39..61
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362101"
FT TRANSMEM 106..135
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362101"
FT TRANSMEM 147..172
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362101"
FT TRANSMEM 217..241
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362101"
FT TRANSMEM 247..269
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362101"
FT TRANSMEM 289..315
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362101"
FT TRANSMEM 335..361
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362101"
SQ SEQUENCE 426 AA; 47227 MW; D3B106FA5115DA5B CRC64;
MSSSQRGCLQ QWVSGRLSEH SFIYKIFFGP DPNKVRPKVL LMITFLCIIN IVIWVVAVLV
YKPYPSMIGT GALAYTLGLR HAVDADHISA IDNVTRKLLN DNKHPVSVGL FFSLGHSTIV
FVVAVVVAAT ANAVANGVDH FAEIGGIIGT SISIAFLVLI AALNIIVLAG VLRTLRMVKR
EGIYTEMDIE EHLNNSGLLG RFFRPVFRFV DASWKMYPLG LLFGLGFDTS TEIILLGITA
IQGAKGMSMW LIILLPLLFA SGMSLIDSLD GMLMLFTYTW AYVNPIRKLY YNLTITMISV
VVAALVAVIE FFSLIGQQLG LDNGWWRFWY SLGNSFEWIG IVIVGAFIVT WLVSAVLYRW
LGYRDLEQRF DSEGSNVPPT RTDQIAKTCS IVSDSEKQDN GLIEYLEIEV ATEDLAVDKT
CISSLV
//
