ID   A0A163XQP8_9FLAO        Unreviewed;       935 AA.
AC   A0A163XQP8;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Zinc protease {ECO:0008006|Google:ProtNLM};
GN   ORFNames=AV926_12585 {ECO:0000313|EMBL:KZE78286.1};
OS   Myroides marinus.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Myroides.
OX   NCBI_TaxID=703342 {ECO:0000313|EMBL:KZE78286.1, ECO:0000313|Proteomes:UP000076630};
RN   [1] {ECO:0000313|EMBL:KZE78286.1, ECO:0000313|Proteomes:UP000076630}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L41 {ECO:0000313|EMBL:KZE78286.1,
RC   ECO:0000313|Proteomes:UP000076630};
RA   Hong K.W.;
RT   "Whole genome sequencing of Myroides marinus L41.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KZE78286.1}.
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DR   EMBL; LQNU01000065; KZE78286.1; -; Genomic_DNA.
DR   RefSeq; WP_038984473.1; NZ_LQNU01000065.1.
DR   AlphaFoldDB; A0A163XQP8; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000076630; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   PANTHER; PTHR43690:SF34; ZINC PROTEASE PQQL-LIKE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 3.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670}; Signal {ECO:0000256|SAM:SignalP};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..935
FT                   /note="Zinc protease"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5007847646"
FT   DOMAIN          51..174
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          201..371
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          700..864
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   935 AA;  107139 MW;  218A7829168F929E CRC64;
     MKRTQILYFF ASVLCPLLAV GQSTFSDLPK ADKAIYGTLD NGLNYIIHPI PQQKTEYRLV
     LNVGSLQERD DEKGFAHFLE HMIFNGSDDF PGRQAIDTLQ RLGYQFGRDI NAYTTYERTV
     YDLSLLDIRQ QDLAINILGN FLGKSHLNKE GIEKERRIVI QEIKDFGTEP LFNRKKLENT
     PHANRLPIAT ESDILNLDPI KLKAFYQRWY NPTLATIIIV GNVNTTEAVE QIKKHFGAFK
     GQSNLTRTQS ENTFSPTYTD RLEVQKDSNA TANKLEIIRF SDAPFLANKA DYKQQVIEQV
     YKLWLNHKLS QAKSQTTAHS LWYLPNKNEN ALELKAKTKE ELYSGINLTA SVLNTMTVKG
     IHNEELTRFK QHLLNHSTPT TDEDITYVTN AYVDQVVVNS HYISSVDRHR LLEEVLPEIT
     REDINQKHTA IWDTSKENLY LLTANDRLFS IESAEELDQQ WSEGATKTLV FKKAKKKKSH
     HRPKGAFHWK VMPPIHSENT GTITAEKYYD NLDITELTLS NGLRIGIKPT KATDDNYILT
     MFTRNGLSQI PTDERKYYQD ASYFIDSSWI HGLTHDGYMS VGADREISTL VSINNDASII
     NTSSRKGNTR DLFEWTYRKL YDYIKPKQDF KEYVEESIAA IDTTTAPSSL LSNPSIQIEH
     QIEAYKKGTL LSSEELTTAE DWQKVNLDNF FSLYNQSFAN LNEVYVLIAG NFNAEEIKTK
     ALRYFGSLED HTNKVSQENR NSLKSPLKEV KRVTLSSSDV ERTDVTIVFN GTIQPVLKES
     MMAHIVREMF NNQFLTLSRE KEGLVYSPSS VLEVEIYPNP RTSVSLFFSA TLSDVEKLEQ
     LAMEVINSIQ TQRISESELG QMKRTILNNK KLHLTETSTF QWVDKLRETQ LNFSSLKDFN
     DYETILNSIT PDDLIKVAKS MFTTSSYGVF LVTPK
//