ID   A0A163ZP76_9SYNE        Unreviewed;      1013 AA.
AC   A0A163ZP76;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:KZR86695.1};
GN   ORFNames=MITS9508_02614 {ECO:0000313|EMBL:KZR86695.1};
OS   Synechococcus sp. MIT S9508.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC   Synechococcus.
OX   NCBI_TaxID=1801629 {ECO:0000313|EMBL:KZR86695.1, ECO:0000313|Proteomes:UP000076799};
RN   [1] {ECO:0000313|EMBL:KZR86695.1, ECO:0000313|Proteomes:UP000076799}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MIT S9508 {ECO:0000313|EMBL:KZR86695.1,
RC   ECO:0000313|Proteomes:UP000076799};
RA   Cubillos-Ruiz A., Berta-Thompson J.W., Becker J.W., Chisholm S.W.;
RT   "Evolutionary Radiation of Lanthipeptides in Marine Picocyanobacteria.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KZR86695.1}.
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DR   EMBL; LVHU01000015; KZR86695.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A163ZP76; -.
DR   STRING; 1801629.MITS9508_02614; -.
DR   PATRIC; fig|1801629.3.peg.2826; -.
DR   Proteomes; UP000076799; Unassembled WGS sequence.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          477..547
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
FT   REGION          992..1013
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1013 AA;  113953 MW;  B51658EBF889BFCE CRC64;
     MQPPLQPRRL AWIETFRSRS RLDLLSFWHR CGDFHRQSVL EEPWGAQHRP DWAKRGLLIW
     PRGGVWLRIE QTITWPNHWQ QCDDSLERLV LSWWADQVRL WVDGVLVHEG DLFDTRCRLK
     LPVHWSEGAG LRLLLELRSP CHDDGALITS DLVREPAMPS VDPQACLLPQ ALDLTGIKAK
     TLPESWLDCD PLSTEAVAQV DQHLAGLAHA AGGLHWVGHA HLDLAWLWPV ADTWQAAERT
     FHSALDLMEL FPELHFAHST PALYEWMERH RPALFVRIQQ ASRLGRWEPI NGPWVETDCV
     LVSTASLWRQ FSLGQEASQR LFPEWRHDLA WLPDSFGFGS GLPAVAYATG VRWFCTHKLA
     WNATNVFPHR LFRWRGRGGT ELLALMLPGI GTDADPMAMQ QEQQRFQANT GVDQALWLPG
     VGDHGGGPTR EMLEEMQLWQ DHPQAAPRHA GTVREYLKQL EPLRSALPVW KDELYLELHR
     GCATSRPDQK RHNRTLERLL READLVEALG AKPTQRRDWQ VLLFQQFHDI LPGTSIPEVF
     DQAEPQWRAA RRRVAVLRTA GLHQLLSRAS SADSAPDKAC QRWVWCGLQP LQRWSPLVRL
     PRGRWSCEGN NLPSQVAPGG DLWVQLPEAQ GVMALPLECL PDAPAVASAS VTASPAVRNP
     VRVQLIAEQS WRLCNGLLTL ELDRRGLTRL QDEQGVDQLS EPVQFRRYRD WGEFWDAWDL
     AVDYPQHPLP MAADWQLELV EQGPLVARVV LRSSIESSAL RMDVLLRADS PAVELQITID
     WRQTHELLRV VCPLARSAVR WAADTSGGVI ERPAVALTPS EHARWEVPVI SWLASEEAGP
     GGGLGVLLDG PQGVDAGPHH LGISLLRGPT WPDPSADQRL HRHRLALMPV SRGWYRDGLA
     QEAIRFREPG WLGPVDSCGR WHGFPGLPHQ LVPVSIRPDQ SANAVQHAVL VQLLNPGSAR
     VTWSPGHQGW LIEDGQQSTT ITPGALQELR LAPQSSWSSK GSSSCFDGGP KAV
//