ID A0A164JG84_9NOCA Unreviewed; 566 AA.
AC A0A164JG84;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=AMP-dependent synthetase {ECO:0000313|EMBL:KZM70372.1};
GN ORFNames=AWN90_03560 {ECO:0000313|EMBL:KZM70372.1};
OS Nocardia terpenica.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=455432 {ECO:0000313|EMBL:KZM70372.1, ECO:0000313|Proteomes:UP000076512};
RN [1] {ECO:0000313|EMBL:KZM70372.1, ECO:0000313|Proteomes:UP000076512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 0406 {ECO:0000313|EMBL:KZM70372.1,
RC ECO:0000313|Proteomes:UP000076512};
RA Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA Babar A., Rosenke K.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZM70372.1}.
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DR EMBL; LWGR01000015; KZM70372.1; -; Genomic_DNA.
DR RefSeq; WP_067577616.1; NZ_KV411303.1.
DR AlphaFoldDB; A0A164JG84; -.
DR STRING; 455432.AWN90_03560; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000076512; Unassembled WGS sequence.
DR GO; GO:0016878; F:acid-thiol ligase activity; IEA:UniProt.
DR GO; GO:0016405; F:CoA-ligase activity; IEA:UniProt.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43605:SF10; ACYL-COA SYNTHETASE MEDIUM CHAIN FAMILY MEMBER 3; 1.
DR PANTHER; PTHR43605; ACYL-COENZYME A SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Reference proteome {ECO:0000313|Proteomes:UP000076512}.
FT DOMAIN 48..405
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 455..532
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT REGION 543..566
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..557
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 566 AA; 62483 MW; F67760D286451DF2 CRC64;
MTTNTDRYRA ARDRLIALAT DYDSARASFE WPRLTGVFNW ATDWFDAIAR GNERTALWIV
EEDGRERRVS FDEMARRSDL VAAWLAELGV RKGDRVLLML GNQVELWESM LAIAKLGAVI
MPTTAALGPA DLTDRIDRGA VCFVIANAAD TAKFADVGGE YTRIAVGGPV DGWHRYAEAD
AVADPGPFTA VTDVDDPLLV YFTSGTTSRP KMVQHTQISY PVGHLTTMYW IGVRPGDVHL
AISAPGWAKH AWSCLFAPWL AEATIFVYNY TRFDAAALLT QLHRARVNTF CAPPTVWRML
IQADLGTRPP ELREILGAGE PLNPDVIARV EKGWGLTIRD GFGQTETTLQ VGNTPGQPVK
PGSMGRPAPG VPVVLVDPIT GERADEGEIC LDLSERPVNL MTGYLQDPER NAAVLAGGYY
HSGDVATRDA DGYITYIGRT DDVFKSSDYK VSPFEVESVL IEHPAVVEAA VVPQPDATRL
AVPKAYVTLA AGWEPDRETA RAILEYARDH LAPYLRVRRV EFAELPKTIS GKIRRVELRR
REERAHASGD PLHTEYRYED VIPPTA
//
