ID A0A164MHJ1_9NOCA Unreviewed; 2088 AA.
AC A0A164MHJ1;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=AWN90_32435 {ECO:0000313|EMBL:KZM73363.1};
OS Nocardia terpenica.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=455432 {ECO:0000313|EMBL:KZM73363.1, ECO:0000313|Proteomes:UP000076512};
RN [1] {ECO:0000313|EMBL:KZM73363.1, ECO:0000313|Proteomes:UP000076512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 0406 {ECO:0000313|EMBL:KZM73363.1,
RC ECO:0000313|Proteomes:UP000076512};
RA Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA Babar A., Rosenke K.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZM73363.1}.
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DR EMBL; LWGR01000007; KZM73363.1; -; Genomic_DNA.
DR RefSeq; WP_067590584.1; NZ_KV411304.1.
DR STRING; 455432.AWN90_32435; -.
DR OrthoDB; 4510129at2; -.
DR UniPathway; UPA00011; -.
DR Proteomes; UP000076512; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 2.
DR CDD; cd19540; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 4.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 2.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF13193; AMP-binding_C; 2.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 2.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000076512}.
FT DOMAIN 943..1018
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2000..2075
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2088 AA; 222160 MW; 31AC61192DD5E071 CRC64;
MRAPGRLRLS SAQEALWLAQ KIRPEVPNII AMYWDIDGEI DVVTMREALA DVVAEIRPFL
VNFGEDEHGS YQFRRDDHPV APVVADVGGR ADPVAAARAI VAGNAGATVD LGTGDLMRLG
IVALGPARYF AFLAVHHLLM DGYGTVLFMR RVAQVYTAKC QGARAVPTAF GGPEDVNDAD
RCYLESAVAA ADGRFWSERL AGVPEPVTVA RHHDADRTGV VGYRLDIPAA EAARWLTGAT
EVGLWLPDYL TAGVAVLVQR LTGADDFVVR FAVANRSGAA RLQPGVHANF APLWVSARPD
TVFAALAAHI GDDLRAAVEH ARYPISTVLA DAGWSGRGGL GPAVNVIPFT EVLEFAGSPG
HLEVQSVGAV DDLLITVYED QRRAGLVVRF DGNAATYSEN DLAVLAERFL AVLHQVTADP
RIAIGRVDVV TDRERDLLRR WSESEAPQPD STVPELFAAQ VARSPGAVAV VSGDIEVTYL
ELADRADRLA GALRGRGVGA GSVVAVALPR SVDLVVALLA VLRAGAAYLP IDPNYASERV
SFVLADAAPA LLISDSGTLK VLPDTEIPVL RIDDAAYPPV AGLGNGPRPG DLAYVIYTSG
STGTPKGVAV EHRTVANLVP QMRSRMGLEP GTRMLAGTSV GFDVSVFEIF APLCTGGTVE
LVRDILALTE SGARTGGAIS TVPSAFAEVI DRTDGAIAPA VVVFAGEALP MDLVRRVRTT
MPGATVVNGY GPTETFYCTS HIVGAADLGE TSVPIGTPLG SNRASVLGPG LLPVPIGATG
ELYVSGAGLA RGYRGRPGMT ASRFVADPSD PAGGRMYRTG DLVRWGGDGL LRYVGRADDQ
VKIRGFRIEP GEIEAVLVSH PAVARAAVLA HAVAGEPTLV AYVVAERTAL DGGELRRFAS
TRLPGYMVPS AIVVLDRMPL TANGKLDRRA LPEPVFAAAE YRAPEGVEQE ALAAIFAEVL
GVERVGMDDD FFDLGGHSLR AARLAARIRA VLGVEVTIRQ IFDTPTVATL LERIDRQAAV
RPALIRRPGA DPVPLSFAQH RLWFLDRFEG SSATYNIPLV LRLTGRLDVP ALRAAVADVV
MRHESLRTVV VPDGDGAAFA RVLPAESVAV PVSEMEVAAA ELNSAIEART RYTFDLTAEI
PIRVSVLRSG PEEFAVLLLM HHIAADGWSM AALTRDVSTA YTARRAGNGP EWSALPVRYS
DYAVWQRELL GSESDPDSVL ARQFEYWRAE LAGVPQPLRL PLDRPRPQAL SYRGDATRFV
VDAALYNAVG DLAGRRGVTI AMVWQATLAV VLYQLGAGED IVVGSPIAGR VDDAVTDLVG
LFINTWVLRV DLSGNPSFAT VLERVRGKAL AAYDNQDAPF ERLVELLNPE RSTAYTPLFQ
VMLAWHNTPL PELALPGVHG TAEIADAGTA RFDLSFDLVE DVDADGGRVV RGRIEFATDL
FDRATVEALG RRFLTVVRAA VADPEVPVGR IDIRTAEERE LLRRWNDTAA ELPVTTLADL
FAAQVGRSPG TVAVVDGDTE LTYAELADRV ERLARVLRGQ GVGIESVVAV ALPRSVDLVV
ALLAVHRSGG AYLPIDPKYP SQRLEFILAD AAPALLVSDG ETRKSLPHTG IPELLLDALP
FDAGSDARFE ALSPRTLAYV IYTSGSTGRP KGVAVEHGSA VAFVAQVATR LRVAAGTRVL
ASTSVSFDVS VLEIFGALCT GGTLDLIPDI LALGELRSWS GGVISTVPSV FAELLDRLDG
SIEAGTIVFI GEQLPLSLAR RVQAAIPGAV IVNGYGPTET TVASTEYALP AGSGLTGDPG
ESTARSVPIG TALGGERVHV LGPGLVPVPV GVVGELYIAG AGVGRGYRGR GGSTALRFVA
DPFDSMGGRM YRTGDLVRWG RDGLLRYVGR VDDQVKIRGF RIEPGEIETV LETHPAVART
VVVARGRNGS ADRQLVAYVV AVEGTAPDSD ELRRFTGARL PEYMVPAAVV VLEGLPLTAN
GKLDRRALPD PVFTAGEYRA PRTEQEKTLA AIFADVLGVE RIGLDDNFFT LGGQSVLAAR
LVGRIRSVLG VEVPIRLVFE APTVAGLAER WTDLIATRRP QLRSRERR
//
