ID A0A164N7E7_9NOCA Unreviewed; 446 AA.
AC A0A164N7E7;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Dioxygenase {ECO:0000256|RuleBase:RU364048};
DE EC=1.13.11.- {ECO:0000256|RuleBase:RU364048};
GN ORFNames=AWN90_32155 {ECO:0000313|EMBL:KZM74059.1};
OS Nocardia terpenica.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=455432 {ECO:0000313|EMBL:KZM74059.1, ECO:0000313|Proteomes:UP000076512};
RN [1] {ECO:0000313|EMBL:KZM74059.1, ECO:0000313|Proteomes:UP000076512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 0406 {ECO:0000313|EMBL:KZM74059.1,
RC ECO:0000313|Proteomes:UP000076512};
RA Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA Babar A., Rosenke K.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1,
CC ECO:0000256|RuleBase:RU364048};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1,
CC ECO:0000256|RuleBase:RU364048};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787, ECO:0000256|RuleBase:RU364048}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZM74059.1}.
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DR EMBL; LWGR01000007; KZM74059.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A164N7E7; -.
DR Proteomes; UP000076512; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF89; CAROTENOID 9,10(9',10')-CLEAVAGE DIOXYGENASE 1; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000256|RuleBase:RU364048};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU364048};
KW Reference proteome {ECO:0000313|Proteomes:UP000076512}.
FT BINDING 158
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 206
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 267
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 439
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 446 AA; 49329 MW; 6F78141935A4C80A CRC64;
MTSDDDVPLH LAGNNAPVTE EVTVGPSEVV GVIPEELNGV YLRNGPNPRT GWSPHWFAGD
GMVHAVALSG GKACWYRNRY VRTPLYRHGG QSRFALAVDP VTGQVDYRVT TANTHVVAHA
GRLLALEEGG LPYEITPELE TVGPFTFGGA LQAPMTAHPK RCPRTGELLF FGYRVRPPYL
TYYRAAPTGE LLLAQVVPIP RAVMMHDFAI TDRHAIFMDL PVVFDPRAGV GGLPWRWDDD
HRARFGVIAR GGGPVRWFDI EPCYVWHTMN ACEGDGAITV TGCRVPTLWR AGPDDLAGGL
PRLYQWRLEP ATGRVVEQPL DDVPIEYPRV ADADVGQRYR YGYVTSFALE PVPERSQIYR
YDFTDRTSRR AHRLPAGHTC SEAVFVPRPG AGDDNGYLIA FAHNHFRGTS YLLILDATDL
TAPPVAEVHL PVRVPAGFHG TWLPDH
//
