ID A0A164PZL0_9CRUS Unreviewed; 534 AA.
AC A0A164PZL0;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 08-NOV-2023, entry version 14.
DE SubName: Full=Beta,beta-carotene 15,15'-dioxygenase {ECO:0000313|EMBL:KZS07296.1};
GN ORFNames=APZ42_028984 {ECO:0000313|EMBL:KZS07296.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS07296.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS07296.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS07296.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS07296.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS07296.1}.
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DR EMBL; LRGB01002490; KZS07296.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A164PZL0; -.
DR STRING; 35525.A0A164PZL0; -.
DR EnsemblMetazoa; XM_032937856.2; XP_032793747.2; LOC116930445.
DR EnsemblMetazoa; XM_045179136.1; XP_045035071.1; LOC123475909.
DR OrthoDB; 294919at2759; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF24; CAROTENOID ISOMEROOXYGENASE; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000313|EMBL:KZS07296.1};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Oxidoreductase {ECO:0000313|EMBL:KZS07296.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858}.
FT BINDING 184
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 240
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 311
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 521
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 534 AA; 60468 MW; EAF6831740B4A64B CRC64;
MSEKIEHLSS WIRTLDVETE SPIEGMIVGK IPEWLEGSLI RNGSGMFEIG ETKMNHLFDG
LSVMHRFAIN GYGEGKSTYQ NRILQSDTYK QAKAANRLTM HQFGTFAFPD PCQSLWGRFM
ARFEPVTKTE KTDNCCVSVC YLGDKLYAFT ETPQIRQVDA ETLETVGEKC NISELVAVNH
STAHPHVLED GTVYNMGNSV GSKGPIYNII EFPTGAGALE GAKIVASFPS RWKMSHSYYH
SFGITENYFV FLEFPLILNT AKLLAMNLRQ KAVDSSLDWF PTEKTRILLV ERKSGELVDT
IYEAPPFFCF HHGNCYEKNG YIIMDISHCK DATIFAGLSL KSLRENRGDF TNTYYTRFVL
PLGVEPPIGN DFQDCKNLVE VEGSKCKSYW QSNKIIFCEH ERLLEQSLEL PRINYSRNGK
EYRYVYGISQ LDGYAEPEKI LKLDLNTREV KQWAKAGFSP SEPVYVSRPE SIEEDDGVLL
FSAVDQVNPK KVLLIILNAA TFKEEAVVEY VASGIITKDF HGIFSRKGDV VHGY
//
