ID A0A164QEG2_9CRUS Unreviewed; 1233 AA.
AC A0A164QEG2;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Short transient receptor potential channel 6 {ECO:0000313|EMBL:KZS07680.1};
GN ORFNames=APZ42_028775 {ECO:0000313|EMBL:KZS07680.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS07680.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS07680.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS07680.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS07680.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS07680.1}.
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DR EMBL; LRGB01002451; KZS07680.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A164QEG2; -.
DR STRING; 35525.A0A164QEG2; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0034703; C:cation channel complex; IEA:UniProt.
DR GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR013555; TRP_dom.
DR InterPro; IPR002153; TRPC_channel.
DR NCBIfam; TIGR00870; trp; 1.
DR PANTHER; PTHR10117; TRANSIENT RECEPTOR POTENTIAL CHANNEL; 1.
DR PANTHER; PTHR10117:SF47; TRANSIENT-RECEPTOR-POTENTIAL-LIKE PROTEIN; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF08344; TRP_2; 1.
DR PRINTS; PR01097; TRNSRECEPTRP.
DR SMART; SM00248; ANK; 2.
DR SMART; SM01420; TRP_2; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:KZS07680.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 348..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 563..585
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 650..672
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 154..186
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 189..251
FT /note="Transient receptor ion channel"
FT /evidence="ECO:0000259|SMART:SM01420"
FT REGION 845..871
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 971..991
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1007..1077
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1111..1130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1192..1233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 851..868
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1007..1049
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1058..1077
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1192..1214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1218..1233
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1233 AA; 137930 MW; E23685B996910389 CRC64;
MEKPPKDMVP QFDSVEEGCL RTESFRDLKM PILPKSLTLE EKKFLLAVER GDLATVKRII
HRVKRGLHGN SINLDCMDPL GRGALLMAID NENLQMVELL VVMGVATRDA LLHAIDKEFV
EAVELLLEHE ELIHKEGEPY SWENVDRTTS SFTPDITPLI LAAHRNNYEI LKILLDRGAT
IPIPHDVQCG CSDCIRGVLE DSLRHSMSRI NAYRALSSPS LIALSSNDPI LSAFELSCEL
KRLAYLETEF RQEYMDLRRQ CQQFACDLLS HTRSSSELAF LLNHDPSNNA RRSPSTDDYQ
EMKLARLELA IEQKQKKFVA HPNIQQLLAA IWYEGLPGFR RKSAIDKVAE ITLVALLFPL
YCGLYMIAPL SSYAQLMQKP FMKFLIHASS YLFFLFLLIL VSQRFDVLVI ELFGTESMRK
TLEDQLRRQR GNLPTFLECF VAVYVLGYVY EEIYEMWKTG VGRYIRNLWN VIDVCRDLSY
LLAMGLRVVA YVQQQQEIQA NPAAAYIPRE EWDAFDPQLV AEGVFAMANI FSALKLVHLF
SINPYLGPLQ ISLGRMVIDI VKFFFIYTLV LFAFACGLNQ LLWYFSDLEK KKCYTLPGGL
PDWSKNADAC AKWRRFANLF ESSQSLFWAS FGLMDLGNFE LAGVKSYTRF WGMLIFGAYS
VINVVVLLNL LIAMMSNSYS LITEHSDTEW KFARSKLWMS YFDATGHTLP PPFNLLPTPK
KIMRLFCHKS NASNPKLRRT STKGRHANER DYCYTAVMRS LVWRYVTAMH RQQEMSQVTE
DDVNEVKGDI STLRFELLDV FKNNGMDISS ANKNSKAALG RKMRIWERRL LRDFHVVSVA
GADEEVDQES SSTDGMGITR SLSSGGNEAK GNAADRFRKL ASVAVAMNAA GISQGIAAGQ
GRTIKPLSQI GRSMSNESFK SSQNLRKAME EAQRLTVVAP TPEPSPQHGK YSPDIALVAD
SGSSVLQLLR SMSEQEDEEE EEDREDNEQK PKEFTFFSAN KKVNQLPTPT VTVSQTSSSV
TSSSVPAKQN EVKGSSSIME SNSKQLRSIK KAPSPPLPDT KASNTSNAIE TPNSQSLTAL
LTKMEAKPLQ SNGLSENKVT VESEVQRLDT VPTNVGASGP TLSAMNKESS VPLTGQDISY
ATTVSNAEAT LTDDAPPSNC AASKSVPITL PKEQSTIVMP DPVVTDRKLA IQSQNASVMP
NAGMQPNSPN AEEKQPSAGD AKTVKRESSK GWF
//
