ID A0A164V5N7_9CRUS Unreviewed; 2022 AA.
AC A0A164V5N7;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN ORFNames=APZ42_023170 {ECO:0000313|EMBL:KZS11992.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS11992.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS11992.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS11992.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS11992.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS11992.1}.
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DR EMBL; LRGB01001411; KZS11992.1; -; Genomic_DNA.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0042575; C:DNA polymerase complex; IEA:UniProt.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0071897; P:DNA biosynthetic process; IEA:UniProt.
DR CDD; cd01650; RT_nLTR_like; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR003656; Znf_BED.
DR PANTHER; PTHR47501:SF6; TRANSPOSASE; 1.
DR PANTHER; PTHR47501; TRANSPOSASE-RELATED; 1.
DR Pfam; PF14529; Exo_endo_phos_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF02892; zf-BED; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 825..1095
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 1256..1280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1618..1671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 269..325
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1263..1278
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1618..1643
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2022 AA; 227865 MW; 9B2FE55A06889915 CRC64;
MYRSNLMNNR SPPRKKPCND EINLPPVIIK LADDYIIQHA GDPKDSTVLT GGDLAVYAHN
EDQQTSLLSL KELMNRPVIC SLPLSSKTNR VGVIFGVPTS DTIEDLQDAL TDQNVTHVKR
LPMRGNPEMP SETVLLTFST PLPPRVKIAF LSFQVQISFP NQYRCLKCWR LGHTAARCNA
TQSCCRKCGR QHPLEQDCVT RCVNCPSPSH DSSHYDCPAY LEMKKILKMA YLEGIPVGEA
RKRVSNLTSI SAHRSGPPTH QEIARTPEIS QLKAQLEAVQ EEMKQLKEST IPQMSKEIED
LAEDLLETKE KIANYNQRFD TLEKKSVIKC KQPIAQKTWT TAAANMTSLT NPNFKCLQWN
VRGLTKAKLE EFRNFLSLVN PEVALLSETH WNSGFAPKLG GGVAILIRKT LHFTPIHLHT
RDTVEAIDAS VICTNKKQID FISTYVPKGD CEMEDIEDLL NRTNDFVIGG DFNGHHSLWK
TDTNENKAGR SINEALANSD NACLITPVNL NTRIDPATGK STTIDLTFTS PALVTSATTI
PGPYMGSDHL PIITTINAAP SRSSNRPVTC IIDEDKWPPW NQHMDGLLAK HNFTTITDPE
TAFKTLMDSL EESNAKYLKK TDPTRQPEAC KDPARPWWNE ACKNFVKAAR RAFREWRESP
LSLSKREKWK KAEAEKRRSI IKAKKEAWNT FVSSLGPNDQ PKMWAFVKNM AGKGSDSFAD
GCAIILNDTV YSIPQEKSEL FLEKFNNIHP KNIPTNRIFE ATISNTINSQ SPNILNDQIT
PEEVERAIPK SRSNATGLDK DLIQNKMLQN LSSANKAHLL HLFNTLLSNK FVPAQWKTAV
VIPLVKQGKP TEDPNSYRPV SLTSCLGKTF EKILSNRLHW YLETKCAINV TQAGFRRGCS
TADHIAQLDS DVKLSFNMKQ CTVATFLDIK KAYDTVWIQG LIYKMAKTGV SGPFLGWIQE
FLSGRSMCVR IGNNTSQTRS VENGVPQGAA LNPILFNIML IDFPSSTPET RILLYADDVT
LYTQARRPKD AELTLQPVLD RVYRWGQKWK FTFAPEKCAM MVFTRAYKPG NDPLLFLNGH
RIQSQPTFKF LGVWFDSKLI WKPHINYVAN RCSRLKNLFA IMAQTKPGPT AKTLIMLYKS
LVRSVTDYGS ISYGSASKSN LRKIDVIGRT ILRTILGTRQ YTPIEILYAE TDTEPLHSRT
SWLTRKYLVH LSYKPRNPMY APAKHLVSAT YEWKPRSTPG IIREARHLES KGITLFPPQS
EVPSEYKHPP PSRPPPGRTA WCPLSKKMAL TCRAKTVAKD ISPEDDSDES SALDNYPESE
EAILPNSTAP SATAVSEDES DGNKWYNSLS LSYFTFGAQL KKTRPMPHEN IKGQCKKCNK
TVSGRISSTT NWINHLKKAH PTLHTGYIKD KELKRNLDPS NPVPAKKIAG RLKRERTRQS
KLEFKSAKTP SRLPAFLQKK IDVLIMNYVI SNARPVSTVD DTAFMAMIIG LNSKASVMGA
KKLRRMIENE RKVFEEEVTA AMSSVANVCL TADMWSTTHR SWIGMTSHWL HEKTLEKKSA
VLCCKRIKGS NTYDLISGLI EEQINKFKIG GKVVCIVTDN GANIRKAVRS MQDCAEQREN
ARRLDSMEAA KAKRQEKAGN KSGKSKAKKV KQSTSENNPS KTNESMMEVD DTETEVDDDM
VYLDLDIELD EDFIENEMRE LLVAEILKEV VVAATYDYDI PAKLCEDIPC TSHSLDLVAT
VDFQKVLDAI RPVTFKSCQL KTPVVTRWNS EYDSVIFIME QDQVKLDGVF KKLKLVPLNV
GDRILLKEYL AVMGPIAIYL DVMQGERNTY LGCVIPCITK IKSAIANVTD IAPNGYGANI
RRGLMNHINR RFDPILKKES FMLATALHPR FKLNWIPKED EELASDVRRL LEQKLEELCP
LDSTTNVRAQ TETDDLLYIP SKATPYMNEL DLFMVDPDIN LESLHKYPRI KALCLRFNTA
LPSSAPVERL FSAGPLILTA RLNRLSDEFF ETLLILKIHK SV
//
