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Database: UniProt
Entry: A0A164VLS5_9CRUS
LinkDB: A0A164VLS5_9CRUS
Original site: A0A164VLS5_9CRUS 
ID   A0A164VLS5_9CRUS        Unreviewed;       500 AA.
AC   A0A164VLS5;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   08-MAY-2019, entry version 12.
DE   RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305};
DE            EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305};
GN   ORFNames=APZ42_022569 {ECO:0000313|EMBL:KZS12448.1};
OS   Daphnia magna.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC   Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX   NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS12448.1, ECO:0000313|Proteomes:UP000076858};
RN   [1] {ECO:0000313|EMBL:KZS12448.1, ECO:0000313|Proteomes:UP000076858}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Xinb3 {ECO:0000313|EMBL:KZS12448.1,
RC   ECO:0000313|Proteomes:UP000076858};
RC   TISSUE=Complete organism {ECO:0000313|EMBL:KZS12448.1};
RA   Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT   "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Thiol-dependent hydrolysis of ester, thioester, amide,
CC         peptide and isopeptide bonds formed by the C-terminal Gly of
CC         ubiquitin (a 76-residue protein attached to proteins as an
CC         intracellular targeting signal).; EC=3.4.19.12;
CC         Evidence={ECO:0000256|SAAS:SAAS01117307};
CC   -!- SIMILARITY: Belongs to the peptidase C19 family.
CC       {ECO:0000256|SAAS:SAAS01045498}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KZS12448.1}.
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DR   EMBL; LRGB01001361; KZS12448.1; -; Genomic_DNA.
DR   EnsemblMetazoa; KZS12448; KZS12448; APZ42_022569.
DR   Proteomes; UP000076858; Unassembled WGS sequence.
DR   GO; GO:0036459; F:thiol-dependent ubiquitinyl hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016579; P:protein deubiquitination; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001394; Peptidase_C19_UCH.
DR   InterPro; IPR018200; USP_CS.
DR   InterPro; IPR028889; USP_dom.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR001607; Znf_UBP.
DR   Pfam; PF00443; UCH; 1.
DR   Pfam; PF02148; zf-UBP; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   PROSITE; PS00972; USP_1; 1.
DR   PROSITE; PS00973; USP_2; 1.
DR   PROSITE; PS50235; USP_3; 1.
DR   PROSITE; PS50271; ZF_UBP; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000076858};
KW   Hydrolase {ECO:0000256|SAAS:SAAS01044238,
KW   ECO:0000313|EMBL:KZS12448.1};
KW   Metal-binding {ECO:0000256|SAAS:SAAS01044152};
KW   Protease {ECO:0000256|SAAS:SAAS01044292};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW   Thiol protease {ECO:0000256|SAAS:SAAS01044269};
KW   Ubl conjugation pathway {ECO:0000256|SAAS:SAAS01044331};
KW   Zinc {ECO:0000256|SAAS:SAAS01044373};
KW   Zinc-finger {ECO:0000256|SAAS:SAAS01044352}.
FT   DOMAIN       32     92       UBP-type. {ECO:0000259|PROSITE:PS50271}.
FT   DOMAIN      147    495       USP. {ECO:0000259|PROSITE:PS50235}.
FT   ZN_FING      32     92       UBP-type. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00502}.
SQ   SEQUENCE   500 AA;  57165 MW;  7B7EBEA2189A3267 CRC64;
     MSAHGCLHLN NFKAAKGTRP YRLIHSFFAK SCLCHVCQRR GPRLHACLHC IFFGCYGAGH
     IQAHSQQRKH FLAVDLTYGV VCCFQCGDYV YDRELEIIAQ KHQTKASLSL GLGQVYHSWE
     PSEEEVELLK KHTRRKKITD SSIIGLRGLV NLGNTCFMNC IVQALLKVPL LRDFFLSDRH
     ICQFQDEPGR CLVCEISRLF QEFYSGNKAP LTLHRLLHLI WTHARHLAGY EQQDAHEFFI
     ATLDVLHRHC RGPNEQQSTQ PQENSVNRCT CIIDKIFTGG LQSDVVCQAC HGVSTTVDPF
     WDISLDLGPS PSTKVVTTGS GPGSIPTSLQ DCLERFTRAE HLGSSAKIKC SRCLSYQEST
     KQLTMKKLPV VASFHLKRFE HSNRFHKKIS SFIAFPEYLD MSPFMSHRRN INNNVNSNSS
     DRADRPVHKP LISTENMYSL FAVINHVGTI EAGHYTAYIR QHRDHWFKCD DHLITKADIR
     DVLQSEGYLL FYHKMILEYE
//
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