ID A0A164VN48_9CRUS Unreviewed; 408 AA.
AC A0A164VN48;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Sorting nexin {ECO:0000256|PIRNR:PIRNR036924};
GN ORFNames=APZ42_022618 {ECO:0000313|EMBL:KZS12485.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS12485.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS12485.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS12485.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS12485.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in several stages of intracellular trafficking.
CC {ECO:0000256|PIRNR:PIRNR036924}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883, ECO:0000256|PIRNR:PIRNR036924}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS12485.1}.
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DR EMBL; LRGB01001361; KZS12485.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A164VN48; -.
DR STRING; 35525.A0A164VN48; -.
DR EnsemblMetazoa; XM_032935146.2; XP_032791037.2; LOC116928072.
DR OrthoDB; 5398040at2759; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd07621; BAR_SNX5_6; 1.
DR CDD; cd06892; PX_SNX5_like; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR014637; SNX5/SNX6/SNX32.
DR InterPro; IPR015404; Vps5_C.
DR PANTHER; PTHR45850:SF1; SORTING NEXIN 6, ISOFORM B; 1.
DR PANTHER; PTHR45850; SORTING NEXIN FAMILY MEMBER; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF09325; Vps5; 1.
DR PIRSF; PIRSF036924; Snx5_Snx6; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Protein transport {ECO:0000256|PIRNR:PIRNR036924};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR036924}.
FT DOMAIN 21..168
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 316..343
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 408 AA; 47364 MW; 7856A17D9DC30FA6 CRC64;
MENSNNHLDV EKKSERSETV DLNDNTLQVD ISDALSEREK VKFTVHTKTT LKDFAKQDFS
VVRQHEEFIW LHDRFEENES YAGYIIPPPP PRPDFDSSRE KLQKLGEGEG SMTAEEFKKM
KQELEAEYLA TFKKTVAMHE VFLCRLANHP IFRADTNFRV FLEYEQDLSV RGKNKKEKLE
TFLRSFSKTT DEILLGSTQK DVDEFFDKEK SFLLDYHSLL KDATLRADKM TKAHKDVADH
YIKISSCLLE MATADTNQLE RFATKTADIF EKARKIENRV STDEDLKLSD TLRYYMRDTT
AAKNLLYRRL RCLADYEGAN RALEKARAKN KDVHAALEVA DAEWSQHQAC EKFEQMSAKG
KEELIDFKVR RVAAIKKNLV ELCELELKHA NTHSQLLKAS IVALREEL
//
