ID A0A164X6L5_DAUCS Unreviewed; 193 AA.
AC A0A164X6L5;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Calcium load-activated calcium channel {ECO:0000256|PIRNR:PIRNR023322};
DE Short=CLAC channel {ECO:0000256|PIRNR:PIRNR023322};
GN ORFNames=DCAR_019862 {ECO:0000313|EMBL:KZM92773.1};
OS Daucus carota subsp. sativus (Carrot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Apiales; Apiaceae; Apioideae; Scandiceae; Daucinae;
OC Daucus; Daucus sect. Daucus.
OX NCBI_TaxID=79200 {ECO:0000313|EMBL:KZM92773.1, ECO:0000313|Proteomes:UP000077755};
RN [1] {ECO:0000313|EMBL:KZM92773.1, ECO:0000313|Proteomes:UP000077755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DH1 {ECO:0000313|Proteomes:UP000077755};
RC TISSUE=Leaf {ECO:0000313|EMBL:KZM92773.1};
RX PubMed=27158781; DOI=10.1038/ng.3565;
RA Iorizzo M., Ellison S., Senalik D., Zeng P., Satapoomin P., Huang J.,
RA Bowman M., Iovene M., Sanseverino W., Cavagnaro P., Yildiz M.,
RA Macko-Podgorni A., Moranska E., Grzebelus E., Grzebelus D., Ashrafi H.,
RA Zheng Z., Cheng S., Spooner D., Van Deynze A., Simon P.;
RT "A high-quality carrot genome assembly provides new insights into
RT carotenoid accumulation and asterid genome evolution.";
RL Nat. Genet. 48:657-666(2016).
CC -!- FUNCTION: Calcium-selective channel required to prevent calcium stores
CC from overfilling. {ECO:0000256|PIRNR:PIRNR023322}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMCO1 family.
CC {ECO:0000256|ARBA:ARBA00006537, ECO:0000256|PIRNR:PIRNR023322}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZM92773.1}.
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DR EMBL; LNRQ01000006; KZM92773.1; -; Genomic_DNA.
DR RefSeq; XP_017254351.1; XM_017398862.1.
DR AlphaFoldDB; A0A164X6L5; -.
DR STRING; 79200.A0A164X6L5; -.
DR EnsemblPlants; KZM92773; KZM92773; DCAR_019862.
DR GeneID; 108224311; -.
DR Gramene; KZM92773; KZM92773; DCAR_019862.
DR KEGG; dcr:108224311; -.
DR OMA; GMFGDFK; -.
DR OrthoDB; 313692at2759; -.
DR Proteomes; UP000077755; Chromosome 6.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; IEA:UniProtKB-UniRule.
DR InterPro; IPR002809; EMC3/TMCO1.
DR InterPro; IPR008559; TMCO1.
DR PANTHER; PTHR20917:SF0; CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL; 1.
DR PANTHER; PTHR20917; PNAS-RELATED; 1.
DR Pfam; PF01956; EMC3_TMCO1; 1.
DR PIRSF; PIRSF023322; DUF841_euk; 1.
DR SMART; SM01415; DUF106; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PIRNR:PIRNR023322};
KW Calcium channel {ECO:0000256|ARBA:ARBA00022673,
KW ECO:0000256|PIRNR:PIRNR023322};
KW Calcium transport {ECO:0000256|ARBA:ARBA00022568};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Endoplasmic reticulum {ECO:0000256|PIRNR:PIRNR023322};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR023322};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR023322};
KW Reference proteome {ECO:0000313|Proteomes:UP000077755};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR023322}.
FT TRANSMEM 15..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 193 AA; 21272 MW; C14CFC53DC1A6481 CRC64;
MASNVFTQFK YSDSLTVVGI SICTAIVCEA ISWLLIYRTS SYKSLKSTID KASKKLETMK
TDPTAPKISA KKSKTKKIDR VETSLKESSR DLSLFKFKSG AVVALVLFVV FGFLNNLFEG
KAVAKLPFVP IKLVQKMSHR GLQGEDFTDC SMAFLYFLCS ISIRTNLQKF LGFSPPRGAA
GAGLFPMPDP KTN
//
