ID A0A164ZAT8_9CRUS Unreviewed; 577 AA.
AC A0A164ZAT8;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Transforming growth factor beta-3 {ECO:0000313|EMBL:KZS16138.1};
GN ORFNames=APZ42_018173 {ECO:0000313|EMBL:KZS16138.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS16138.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS16138.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS16138.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS16138.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS16138.1}.
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DR EMBL; LRGB01000759; KZS16138.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A164ZAT8; -.
DR STRING; 35525.A0A164ZAT8; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13751; TGF_beta_GDF8_like; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF291; LD29161P; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..577
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007854803"
FT DOMAIN 465..577
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 31..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 278..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 577 AA; 63719 MW; 2F0D8FB3EEADDB24 CRC64;
MADQRRKFLL QSLVLLMAVC WPQQVAGGSA HAAHMKNGDG GKWTAHAHRH HHRVDDPMAS
NNNNNNNNNN QDYVQDMASA SDDNLIDYET DDNAETGSND VNVSDASPLM GVLPEPGTYM
ASNCTSCIQR EELRRRNLEV IKDQILSKLG MQRAPNMTGR LPPRIPPLDH LLDLYGMQGD
APPGRHSAGV HHHAHHQHQQ SDQAFQTGPV YDEEDDDFHA RTEKVIAFSQ LLPQVRQALK
RTESTTTKGM ESIYFKFSDK VTRSSKVDKA HLWLYIQNQQ PPSSGNHGHQ RHHHHHHQQA
QVISKSASAN ASTVWIHIYK VVRVPEGESP VLNPVRMTRV ALPPLLELVD KVPASAGKQQ
SQAQSGGWVS FEVRKVVADW FRWPEDNLGL VVHAVSGDQH APPPPTFNAN GAAAAPAAAT
TPTAASSASS GASKSLPFIV NDHVSADGAL MPFVEVVTTD GRKHRTKRTI GLNCDETSSE
TRCCRYPLTV DFVEFGWDWI IAPKKYEANY CSGECPYVFL QKYPHTHIVQ QANPAGTAGP
CCAPRKMSPI SMLYFDNEFN IIHGNLPGMV VDRCGCS
//
