ID A0A164ZBQ8_DAUCS Unreviewed; 3501 AA.
AC A0A164ZBQ8;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=C2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DCAR_018920 {ECO:0000313|EMBL:KZM95678.1};
OS Daucus carota subsp. sativus (Carrot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Apiales; Apiaceae; Apioideae; Scandiceae; Daucinae;
OC Daucus; Daucus sect. Daucus.
OX NCBI_TaxID=79200 {ECO:0000313|EMBL:KZM95678.1};
RN [1] {ECO:0000313|EMBL:KZM95678.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaf {ECO:0000313|EMBL:KZM95678.1};
RX PubMed=27158781; DOI=10.1038/ng.3565;
RA Iorizzo M., Ellison S., Senalik D., Zeng P., Satapoomin P., Huang J.,
RA Bowman M., Iovene M., Sanseverino W., Cavagnaro P., Yildiz M.,
RA Macko-Podgorni A., Moranska E., Grzebelus E., Grzebelus D., Ashrafi H.,
RA Zheng Z., Cheng S., Spooner D., Van Deynze A., Simon P.;
RT "A high-quality carrot genome assembly provides new insights into
RT carotenoid accumulation and asterid genome evolution.";
RL Nat. Genet. 48:657-666(2016).
CC -!- SIMILARITY: Belongs to the VPS13 family.
CC {ECO:0000256|ARBA:ARBA00006545}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZM95678.1}.
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DR EMBL; LNRQ01000005; KZM95678.1; -; Genomic_DNA.
DR RefSeq; XP_017251625.1; XM_017396136.1.
DR RefSeq; XP_017251626.1; XM_017396137.1.
DR STRING; 79200.A0A164ZBQ8; -.
DR EnsemblPlants; KZM95678; KZM95678; DCAR_018920.
DR GeneID; 108222220; -.
DR Gramene; KZM95678; KZM95678; DCAR_018920.
DR KEGG; dcr:108222220; -.
DR OMA; PYRVDNF; -.
DR OrthoDB; 449127at2759; -.
DR Proteomes; UP000077755; Chromosome 5.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR InterPro; IPR026847; VPS13.
DR InterPro; IPR026854; VPS13-like_N.
DR InterPro; IPR049424; VPS13_C.
DR InterPro; IPR031645; VPS13_DH-like.
DR InterPro; IPR031646; VPS13_extend_chorein.
DR InterPro; IPR031642; VPS13_mid_RBG.
DR InterPro; IPR009543; VPS13_VAB.
DR PANTHER; PTHR16166:SF93; INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13; 1.
DR PANTHER; PTHR16166; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13; 1.
DR Pfam; PF12624; Chorein_N; 1.
DR Pfam; PF21679; VPS13_C; 1.
DR Pfam; PF16909; VPS13_DH-like; 1.
DR Pfam; PF16908; VPS13_ext_chorein; 1.
DR Pfam; PF16910; VPS13_mid_rpt; 1.
DR Pfam; PF06650; VPS13_VAB; 2.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Reference proteome {ECO:0000313|Proteomes:UP000077755};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 2..115
FT /note="Chorein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12624"
FT DOMAIN 136..365
FT /note="Vacuolar protein sorting-associated protein 13
FT extended chorein"
FT /evidence="ECO:0000259|Pfam:PF16908"
FT DOMAIN 588..800
FT /note="VPS13 middle RBG modules"
FT /evidence="ECO:0000259|Pfam:PF16910"
FT DOMAIN 2067..2367
FT /note="Vacuolar protein sorting-associated protein 13 VPS13
FT adaptor binding"
FT /evidence="ECO:0000259|Pfam:PF06650"
FT DOMAIN 2471..2730
FT /note="Vacuolar protein sorting-associated protein 13 VPS13
FT adaptor binding"
FT /evidence="ECO:0000259|Pfam:PF06650"
FT DOMAIN 3056..3224
FT /note="Vacuolar protein sorting-associated protein 13 DH-
FT like"
FT /evidence="ECO:0000259|Pfam:PF16909"
FT DOMAIN 3316..3382
FT /note="Intermembrane lipid transfer protein VPS13 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21679"
FT REGION 2798..2820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3501 AA; 390499 MW; A1030ECFF5A95A30 CRC64;
MFEGLVRQLI VGYLGRYIKD IHKEQLKITL WNEEVKLENV ELILEAFDYL QLPCALKEGR
VGRLSIKIPW KKLGWDPIII SLDDVLVCAC QRNDEEWSKD AVERREFAGK KAKLAAAELA
KLSKRFSDDQ AGTSFISFIT AKILDGIQVS IRNVHVLYRD MLTDGAHVEF GLKFSSLTLM
KQSPAGVSSG KVRGNQVAKL VEVQSLEIYC RTFQRTLDGI RIGNDGTEHV DSTKNLHEGH
INVLAPVDVS ISLLVNRPGN LESDAPQYSI NFTLTGLVIS LDEVQLQEIL NLYDYLSTCR
LRERYGQYRP WASPLSKKVK GWQKLWWQYA QQSVLSDVCK RLRKTSWKYL GERLSRRHKY
VKLYKTKLEC LRQELLLDDD VLWELEQIEK EADIDEILDY RSVAECVIEE FLEDSSSSFG
AKVADVAADN SVDDEHSSSK PRGWLNWLSR GMLGAGGTDD SSQFSGVVSD EVIKDIYEAT
KFYSVPSLGG ETASDEIFLS SVKFNINQIT ATLRSMKHNR AIADLLFEGV FIECKMWEKS
ALVTSTINSA QIVNPSNKQV ILVIRRAITS KHAPELMETS VNIQVDLSPP NHDNELSVKV
MLQSLELTFD LDFILNVMEL YQIIRSFTFQ QERVLLSLNG IDDDKVRLLS KAEYMLSSRK
RVMWDVQIFH NLIGVIWQDT NADTYKMVLE SQALIFRSIR DMGSASSDMS YQPRLFEFQL
SDLYDCFEIK LDDFEINLLL PLNSQMLSIL DKLGVSLTLS SCILPDEPIL KSSEVYIIIS
SLLAHFSLSR YCAILELISN FSALKPAADP AMLKMAASSQ KQFNRARTSN LNCFSVVANL
GSASLLVDLE NGTEHSCILK LSLHELNFRL SIAKLFEWWI GSKALKVITC PIKNEDEIRT
LCSAKATVSN SYAQAHGADG DKNIVIDRDG TSDEKCLLLY YQGRRNSDLN HHKYSIWFND
VDLHFYPYII GQLVGFSDKL AKCGASHVTM ASAAVESCLA KGSGFEIQRF GFSNYFGRNA
DDLDCIPVEQ FPFITSNNDG PLLNLESSLK YAVPEWRDLP KSKERKIRSP RFSFKKQFEQ
IIAQPVDPRS DDEVLPTSLP VDRADMFAVE LNLSSVRLHF HDSASLIGTV TVPTSISSIV
ICDGCFDVLF SCEGVTLSSA WCNQHHSNIL WGSLLPDLPS ILNIRVRKGM NGSLGSMMEL
SISVQHVSCI LPPEYLAILI GYFSISDWRP NAKQHSVAET FELANTETNI NLKFEVLDSA
LFVPAGNDDF HLLKLNIQQL LCSFIENCSS EIVLNDIPVD CLVPVHKVDG KNDCWNISAR
DLSLQLLLLK DDASDFLVSD KSATKIIATL ISELSADVWI RVPCKSVLLS VGSSPLCIMA
RICHIQFTVE GVHVLAGYEI LIDIINQFSS VDADSRGFTS DVEQFLQFKR STKERKGVLA
ESSSVQLTEI KCSFNSVSLK LYTSKCDLPA SVPTFEAETQ FLCYASLRIG EPHYLDISFS
TVSLFSLTNS VRLVECCSSS VVSEFNILTA AVAEIEARVS LPPLDIWFYS SDWSEFIDLC
SSYFKHTPEN PIVKVSSRKS INDLVEQAEN EVDVSNPPQS DSVSSTFASS NMKPGTSLLH
LKSENITTKV HIPVRVSGEL FGEFTELQVH KDSSDMYEAD HYGFIVFTLE SKSSELVFDG
KSAKVKSNIG KINGTVELCK EISERVWRFF QILQVYLEAN ISTQVDLMQI TGEVRCDSID
VWLSHHIFYI CRCIMHGSSS QGSSQFAFGK TDLNLNLRRL SILLIDGKQS SNGPLLEVLL
RHSILCAVCN DNNIQTSFTG DLQVNYNNFH KVLWEPFVEP WKFNLSLKWR NQNSVLLNTA
LMADMSLSST SELNLNVTEP FVEVVFRAID MIADAWGLQG LTSHSASPSF LKNQTKDSIY
NGRYAPYRIQ NLTSLPLAFR VIEGPLSTYY SDASASEDEI VVQPGSSIPI YIDESPEEQL
FRYRPAHSSE RLGDKQFMYT AHRYVTIRLE GTSVPSTPIS MDLVGLSCFH VDFSKSAKSL
KGDAPDGLKT NSVGKNKAEL DSGYVVPVVV DVSVQRYTKL IRLYSTVVLS NATSTPFEVR
FDIPFGVSPK MLDPINPGQE FPLPLHLAES GRMRWRPVGN SYLWSEAYNI SSIIGHENNV
GVLRSVVCYP SHPSSDPFRF CVSVRDMCLP ASGRLKDGTS QYSDNTVKQS FENSRQVMPA
MDESKKYFLH LVTISTPLVV SNFLPVSITL EIESGGVTRS AILTEVENSF FHIDSSHDLA
MVFKIHGYGP SVLKFPRAEK FGAMAKFSGT KFSASETISF NSDLLSEGNL FVSIELIMDA
VSGAREIYIS VPFLLYNCTA FPLVVSNCVS DMKVRGCTLP SCFNLEEDLP PSRKDGLSLL
ISDQDFQITL HNGNLRKSSD NHIVSTRKLL EPHSSTLPGT SYKEIRTVES TARSSANLSG
SSSQSNSKFP DFVEFDHKRV GGCMYSPVSN SSASDIKVQV SRGQPKGHKD SSQNCIWSNP
FSLAPSTGSI RVPVPYPSPN SGYIIAVTST VVTGPISGRT RMITFQPRYV ISNACSRNLY
YKQKGTDSIS HLRVGQHSQI HWADSTLRDL LVSVRFDEPS WQWSGCFLPE HLGDTQLKMR
NHVSGALNMI RVEVQNADVL IGDEKIGGNY SGNSGTNLIL ISDDDTGYMP YRVDNFSKER
LRIYQQKCET FETIVHTYTS CPYAWDEPCL PHRLIVEVPG ERVLGSYALD EVQEFSPVYL
CATSEKPERT LLVYVQAEGA VKVLSVVDSS CHSLNDLKGP RVTSSNVRGK QDKQETSTHD
KEKLSIFIPF IGISVMNSHP QELLYISARN MTVDLGRSID QETFSIQLSS LQIDNQLPST
PYPVILSFEY EIRNNPVGQI RRKDDNTRLT SDSEVEIVDG SCDPVFTLAA AKWRNTDTSL
VSFEYISLKV ADFHLELEQE VIQSVSSFFK TISSRFNGDI LPDGVSMLNL TSEIGLVDIT
STYAQGHEGA ESADQISASN IPIVTGNHKS CSLLPSVVPI GAPWQQIYLL ARTQKKIYVE
LLDLAPINLT LSFSSSPWML MNGVLTSGES VIHRGLMALA DIEGAQIHLN QLLIVHQLAS
WESIQVILIR HYKGQFLHEI YKVFGSAGVI GNPMGFARSV GQGIRDFLSV PAKSLVKNPT
GLFTGMAQGT TSLLSNTVYA ISDATTQFSR AAHKGIVAFT FDDQSAERME KQQFGISSHS
KGVISEILEG LTGLLQSPIR GAERHGLPGI LSGIALGVTG LVARPAASIL EVTGKTALSI
RNRSKLYHMG SHRLRVRLPR PLSRESPLRP YSWEEAIGTS VLSEFDSGLK LKDDILVLCR
RLKQGGKFVI ITERLVLLVS CLSLLDLGKP RFRGIPADPE WVTEAEIGMD SVIHADADNE
VVHIVGSSSD TLSRQKQYHL NRNDRRRWNS SSTPIPLYQT NLEFTCMEEA ENFLQVLLAT
VRKGQEQGWG YVNLLHQSNL K
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