ID A0A164ZPR3_9SYNE Unreviewed; 386 AA.
AC A0A164ZPR3;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Potassium efflux system KefA protein / Small-conductance mechanosensitive channel {ECO:0000313|EMBL:SAY38288.1};
GN ORFNames=FLM9_147 {ECO:0000313|EMBL:SAY38288.1};
OS Candidatus Synechococcus spongiarum.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=431041 {ECO:0000313|EMBL:SAY38288.1, ECO:0000313|Proteomes:UP000182631};
RN [1] {ECO:0000313|Proteomes:UP000182631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA liu f.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; FITM01000018; SAY38288.1; -; Genomic_DNA.
DR RefSeq; WP_074456786.1; NZ_FITM01000018.1.
DR AlphaFoldDB; A0A164ZPR3; -.
DR Proteomes; UP000182631; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30566:SF25; INNER MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR30566; YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000182631};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 176..243
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 253..335
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
FT REGION 348..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 386 AA; 42251 MW; 19E5EF349D1FED3D CRC64;
MPAQELIAAL PVALAKLMGG LLVVWLLGRI GLATATRLTR RTATTTDDFI VRAAHKALVP
MLSMTVVVWA WEGIPYEGIG DRIVTALTGL VTAVVLVQAT NGILVRLLTS AFQRLAKDRD
DDAGFEILTA LKPMLRAVVW VLGGVIYMQS LGVPLGALWA LLSAGGIGAG LALQKPVAEF
FEYIYILLDK PFRNGDFLHV GDSGTWARVE QVGIHSTRLR SVDGELVVMT NSSLANQTLS
NYTVMKRRRR IYRFGVTYDT LPQVLKQIPT MVRAIVEGVK DADFDRCHFV EFGASSLDFE
LCYNIPTNDY VQALDAQQQV NVALVQMFAE QGIEFAFPTR TLYLNAQASG HDSPAGQTTD
KLPQRQTPRP HQFPGEPSTA APPGER
//
