ID A0A165C952_EXIGL Unreviewed; 3144 AA.
AC A0A165C952;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Vacuolar protein sorting-associated protein 13 {ECO:0000313|EMBL:KZV82048.1};
GN ORFNames=EXIGLDRAFT_357035 {ECO:0000313|EMBL:KZV82048.1};
OS Exidia glandulosa HHB12029.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Auriculariales; Exidiaceae; Exidia.
OX NCBI_TaxID=1314781 {ECO:0000313|EMBL:KZV82048.1, ECO:0000313|Proteomes:UP000077266};
RN [1] {ECO:0000313|EMBL:KZV82048.1, ECO:0000313|Proteomes:UP000077266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HHB12029 {ECO:0000313|EMBL:KZV82048.1,
RC ECO:0000313|Proteomes:UP000077266};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
CC -!- SIMILARITY: Belongs to the VPS13 family.
CC {ECO:0000256|ARBA:ARBA00006545}.
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DR EMBL; KV426349; KZV82048.1; -; Genomic_DNA.
DR STRING; 1314781.A0A165C952; -.
DR InParanoid; A0A165C952; -.
DR OrthoDB; 199953at2759; -.
DR Proteomes; UP000077266; Unassembled WGS sequence.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR InterPro; IPR015412; Atg2/VPS13_C.
DR InterPro; IPR026847; VPS13.
DR InterPro; IPR026854; VPS13-like_N.
DR InterPro; IPR049424; VPS13_C.
DR InterPro; IPR031645; VPS13_DH-like.
DR InterPro; IPR031646; VPS13_extend_chorein.
DR InterPro; IPR031642; VPS13_mid_RBG.
DR InterPro; IPR009543; VPS13_VAB.
DR PANTHER; PTHR16166:SF93; INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13; 1.
DR PANTHER; PTHR16166; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13; 1.
DR Pfam; PF09333; ATG2-VPS13_C; 1.
DR Pfam; PF12624; Chorein_N; 1.
DR Pfam; PF21679; VPS13_C; 1.
DR Pfam; PF16909; VPS13_DH-like; 1.
DR Pfam; PF16908; VPS13_ext_chorein; 1.
DR Pfam; PF16910; VPS13_mid_rpt; 1.
DR Pfam; PF06650; VPS13_VAB; 1.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Reference proteome {ECO:0000313|Proteomes:UP000077266};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 11..122
FT /note="Chorein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12624"
FT DOMAIN 147..377
FT /note="Vacuolar protein sorting-associated protein 13
FT extended chorein"
FT /evidence="ECO:0000259|Pfam:PF16908"
FT DOMAIN 599..833
FT /note="VPS13 middle RBG modules"
FT /evidence="ECO:0000259|Pfam:PF16910"
FT DOMAIN 1902..2478
FT /note="Vacuolar protein sorting-associated protein 13 VPS13
FT adaptor binding"
FT /evidence="ECO:0000259|Pfam:PF06650"
FT DOMAIN 2742..2916
FT /note="Vacuolar protein sorting-associated protein 13 DH-
FT like"
FT /evidence="ECO:0000259|Pfam:PF16909"
FT DOMAIN 2922..3002
FT /note="Atg2/VPS13 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09333"
FT DOMAIN 3014..3118
FT /note="Intermembrane lipid transfer protein VPS13 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21679"
FT REGION 1686..1710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3144 AA; 349503 MW; 4A9FF02479BC3F38 CRC64;
MAFLLNGTLK PLITALVNQF VGPYTENIDT DALNANLVSG VGSLSRVRLK KGVFDKFQLP
VDVQEGYLGK LTIELPWQSM FNKPVKIHIE DVYILAVPAA GSQVDPKEDE ERAQAAKQER
LKSAEALQLK VNDPKSGKQD VESQGVLASL ITKVINNIQI TVKNIHVRYE DKLSNPGHPF
AAGITLADFS IVSTDGDWMP AFIASAKEAV HKLASLDSIA IYFDTDAESL AGHTQEETAK
KFNELIAHST AGDLPKHQYI LKPVSGKGRV TINPHLDSQT PKIDVILNFD EIAVGVDDNQ
YRDVISMVDM FHFFIRHNQY RKYRDYAEEQ ASRPKALLQY AGRAILAEVH DKNRRWSWSY
LAERRDDRRK YVHLYKKKTV SSLAAGEVAE LEALERRLTY EDIRFYRSIV DSQVQKDAAA
RRQLEERWKR EHPERKNTGG GGWTGWLWGS GASGGQGANQ PRTIESLSDN ERKELYDALE
YDEKAYVAAS FSTPREAMKL RVVAELNKGL FALRSDPHGR DAEVVSVVFD SFRATFIQRP
ESFEGKFSLG GFSVYDGTTK DTPYHQIVRV KDEHTRAVSM SEGDPEDDKH ANRFFYVKFE
QNPEDERADS VLVVKMRHME IMYHKEFVEA IYNFFKPPES QLESVEALLD AASDTLEGIR
RETRAGLEYA LQTHKTVDVN IEMQAPIIII PEDITTTHCR HLLVDAGHIS VKSNLADKAV
LKQIQQKRKQ PYNEADWKNL EEHMYDKFSL QLKAAQFVIG NDLDSSMRAL HDESQSMHIL
ERINIDLSLE KSILPTNVNL ARMRVSGRLP VLKANFSDAK YKALMRFIDV AVPQLGDSAS
SVQAPVQEDS GPTFRLPPVF SPGAEYNVEL ASPDEEEDPD VQGGEEFFEA SEGVPADLHQ
HSFEVKFKVD RLEAAIAKVG RDGVEKALGD VVLQQFDLGF ALAKFDMKVD IRLRSLSVDT
FTADGKTMSL LTSRDSEANQ ERDLMTITYK RVQRQSPEFM TTFEGIDQSV DVALSTFLVQ
AEPEPVITIY NFIMTTFTSN GPAPPGPAST PAPDVEDNES TLHQAIVLPA PAPAQQQTQQ
STDKLFVHVK LDSFQVVLIN ASTRLATLSL SAADVNVLLN DPTMRVAARL ENMSLTDDAQ
RGQGDNDAQL LSIEGKEVAN FVYETFDVST QPSENSVNSA ITFHAGALKF RFVEEPLHGI
YAFLIKLARL KGLYDAATQA AVQRASEIEV QRMKFDISVQ SPIVIFPWHA REARDVLVVK
LGEIGATNRF EANENRIKAT LRGIQVASTL YYKEEPSTLK IVDDVEIVAD VVQPLRVDRS
RDVVMPDTRV AVKLSDIRLA LTQTQYQLLM SLLQSIPRVF GADGASEASV PSTPVAPPPV
PEKISSTSEA DLIDLQPEIV PSSSASRSVW PSVEVDLAIG AVKLHLYDAN ATDAASLKSS
GIARFALNNN AVRLKMMSNG GMEVEVVLKS FTMGNTYPGA SRFREVIPAA QHERNQFMVL
YSTAGGQDGA ALVVLTVDSP QIIFAVDPLF ALLNFFTNTG DQAVSPMSNA EDEVTAAAAP
SQPSKSTLDI RADLHDVSIS VLESDSDSET QAIQLSIKQV SFSQQTGLTA SIKQLGMSLT
RMNHPSERVS FLDDLDITLA MESRSAAQQQ LASIEVNVEP IIFRASYRDI NLIQSIANKA
IALSTSGEAG KPQSARPTST KKPSSRRIST QLSKRALAPT RFSSARDAPQ LLMTKEQLAA
NFKGFTLILI GDTHEMPIVN LSTKPFIASA KDWSGELHAA TTISTSIQYW NLTNSHWEPL
IEPWTFSALV SKDSADGAMH VTLSSRDRLD INVSSTGVEL ALAQARALMT QETRVLKSAR
GSDAPYKILN RTGCRVRVWT EGENVNAIGL ADGEESDWRF DDWRTVREHV STVGRSHSIG
ILIDGKPWEA ISNVRVDREI ETCYALRTKN DRSKGDAQAT RLLCEVTVVN NVKVVTLRST
YKIENKTLFP VEVAVGIDAQ PYMTHKLAPG KEYALPLDAV THTVRLRPDP GFGYAFSGAI
HWESLVRTPV QTITCLHDSV VRNRNAQADG KEPPFNFHAW AQYDVNDPVA RKYPKMTLKL
HIPIELENLL PFDFDYRVFD KHSRHEWGTF LRKGGIMPVT SVQLNHLVLL NVKIQDPGFK
ASDFAIINTD NASDFEVEKR LPLQDSQGRK LDLRINHMRH PDAGGAFRVQ VYSPYIVVNK
TGLPFAVRAT RVAGGGKEVA GDSGAVLSHP LDKGNEFSFR VGNSSWSKQY INFEAPSADA
GVCIPSSTNR SSEYNIGISW AEGVGKYKLS KVITLAPRFI LKNMLDEPVC FREHGVAPQD
RNVLQPGQRT PIVTFRPEEE PLLTFAYPGL NAKWSSPINV ENIGSVHIRM TPQGDRSEQH
LLRADVLLEG ATIFIVLHRE TGRWPFTVEN ISQFPLKFAQ VDEDRQLSLE DWRNPRSPFA
YTLQPKSAMD YAWDFPASPD KKLALFIGDR VREVDILEIG NLPPFEFPWK EWRGRGRPAV
SVDVRADGKR QVLTVSDFVE EKSLYRRRTA STAGTLSRQD TFTSLGVDAY EVKTQALESA
PSLVFKLDFD GVGLSLLNKR LVEVVYLTMQ GIRVEYTLSQ SAQGIVFSCE NIQIDNQLQE
GLYPVVLQPT PLPRNNGPIR SPPVVQVSLI VLNDNEHGVT FVKYASVLLQ AISVQLDEDF
LFAVYDLTKL KGVSWEEEQE SVLILNAGDI PEPSGAPVEG QDIYFEVLEL QPIQLSVSFM
RTDRVNADEK ISTNNPLAVV LNALTMAVGN INDATLRMNA LAIKDMRLTV PELQTRIIYH
YKQEVLRQLY RVLFSADFIG NPVGLFTNVS SGVKDVFYEP ILGVVHGNTD LGVGIAKGAA
SFVKKTVFGL SDTFTKFTGS VGKGIAAATL DADYQDRRRL NQRRNKPRHA IYGVAAGAEA
FASSFKSGAE GLVMKPIEGA ETGGAFGFFK GVGQGLVGAV TKPVVGVFDL ASNVGEGIRN
TTTVFDKPSR DRARYPRLIP ADGILTSYNP REALGQFWLR DLEHGKYKRE LYVAHIDQPD
DTVVLLTTTR LLAFSSRRLR LAWDLPFAYV KAVNIEPSGI MFKHKEGDYR SQFVHCAKES
TRDWFFKQVA RVVRDHNARK HVDK
//
