ID A0A165E5D8_9APHY Unreviewed; 871 AA.
AC A0A165E5D8;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=RhoGAP-domain-containing protein {ECO:0000313|EMBL:KZT06270.1};
GN ORFNames=LAESUDRAFT_726096 {ECO:0000313|EMBL:KZT06270.1};
OS Laetiporus sulphureus 93-53.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Laetiporus.
OX NCBI_TaxID=1314785 {ECO:0000313|EMBL:KZT06270.1, ECO:0000313|Proteomes:UP000076871};
RN [1] {ECO:0000313|EMBL:KZT06270.1, ECO:0000313|Proteomes:UP000076871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=93-53 {ECO:0000313|EMBL:KZT06270.1,
RC ECO:0000313|Proteomes:UP000076871};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
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DR EMBL; KV427625; KZT06270.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A165E5D8; -.
DR STRING; 1314785.A0A165E5D8; -.
DR InParanoid; A0A165E5D8; -.
DR OrthoDB; 5482027at2759; -.
DR Proteomes; UP000076871; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF129; RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Reference proteome {ECO:0000313|Proteomes:UP000076871}.
FT DOMAIN 9..355
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 392..587
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 169..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..871
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..210
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 611..634
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..686
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 718..751
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..780
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..829
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 848..871
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 871 AA; 97190 MW; 0D2EB5D9A01BCAFA CRC64;
MSSSLESAPS NRPSLSDHPH DAIALFDLHL RFLSDSYLSF FLERKKIEET YVESLHRLHR
KVKAADAILD NPNRNEPSTT RRAWAEIRDN VAREADTRQA FLESLTTDVI TPLISLKETQ
ERIRKRIKED LKEAVTTHAD YAENVLTRLR RNYVKKCQDV DEFKAAIALP YPSPASPPDL
PVSLPTSRRN PSPSPRSNAA SPPPFRPIPD RRPSLGGVST HGRSQSTATA LQDLAHQGKR
QLNQLMTFLD KGGNMKDLAG RSDNALRSVR AKREAEEADK EYRRGVHWLE TLRLRRVKIL
ESGYNSLESF IRESADTVKS TLMKYTDNMI ATAASQSQIC EHGREDILKI SSQRDITIIA
PNIARQLSAS IPKPVYYHNH LVGECRDLIF GVSLVDYATS RNLPEGEVPK IVRICVSEIE
MRGLEAEGIY RVSGRHAAVQ ELQHQIERSE AAFQFNPAID DVYAVASLLK LYLRELPEPL
FKYPLNERIQ HSEELDGHRM NDFQLLRSKL RRLPPVHQAT LKMIVEHLSL VASRADKNKM
DAKNLAIVFS TVIFGEDEMP KGGDLLSVQS WKDTLAEDLI LNVNVLFQSN GSPALPAAPL
GGPVPPASYG SSFTTFGNMP PPSMPSSNRS PRLIRSPSLP PRPSHSYYDA RDMLPDDFTP
QLPSQASHNI HPSRTGPMSS LLTRQSLPPP ERPKLDEHRS YIIQAPLTPS VRSISGDSRR
SSRSKIVPRQ KSREPSPDST LMSRKERWKS PSAMPRMPSR PLTPGGMSSR AGTPSTVYSG
MGTDEFGVRS GAQVVEPRDS SFEEEFPPSA STTSTFASLD TSMSKGSEAI RPPSRNRLVP
NRRPPDNINS AEYFSPQASS IGGRSRRSIS E
//
