ID A0A165GKZ0_9BASI Unreviewed; 682 AA.
AC A0A165GKZ0;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Ras GEF {ECO:0000313|EMBL:KZT58202.1};
GN ORFNames=CALCODRAFT_482590 {ECO:0000313|EMBL:KZT58202.1};
OS Calocera cornea HHB12733.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Dacrymycetes;
OC Dacrymycetales; Dacrymycetaceae; Calocera.
OX NCBI_TaxID=1353952 {ECO:0000313|EMBL:KZT58202.1, ECO:0000313|Proteomes:UP000076842};
RN [1] {ECO:0000313|EMBL:KZT58202.1, ECO:0000313|Proteomes:UP000076842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HHB12733 {ECO:0000313|EMBL:KZT58202.1,
RC ECO:0000313|Proteomes:UP000076842};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
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DR EMBL; KV423954; KZT58202.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A165GKZ0; -.
DR STRING; 1353952.A0A165GKZ0; -.
DR InParanoid; A0A165GKZ0; -.
DR OrthoDB; 68574at2759; -.
DR Proteomes; UP000076842; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF99; RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000076842}.
FT DOMAIN 26..301
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 84..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 473..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..103
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..325
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..343
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..392
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..608
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 682 AA; 73534 MW; 2AD15BE8B5B8894C CRC64;
MHSPTPPSSP SPITPNPNPP TLSSLPPAYI ALALTLLSSQ LFAAVEPRDV LARLAGLRGL
GGEWRREGGV RLGEVDDVRL RGHAEGEAEP GESGKEGETT LAPEQEQRQD TLSRWVESNA
RLGVWASAEV LRGKSRRGRA RALERLIECA EECRALSNHS SMSTLLSSLN APPISRLMHT
WALVSSHHLE LLMKLRDVLP PRTDIARYSE RVELPCVPPL SLFLHTTADT EGPLRLYREI
KRYQSSCALY PQLLEERLAA LPPPQQHQHQ HGAHHSPPVS GTSTPTSPHS GASTPASPHP
PQHAAHTPSP LQATGSGSQS PPQPHHHASH THHAHHSHHA HAHLRSLSGT STPGSLHSIP
EEEGDASLSA SPDSPDSRER SPSLSSASSA PAEYSPGWWG LPDTPLAPLA LQHQLHQLHT
PHLPPPPPPP QAGAREGSYF AYLPHVPRAP SPLRVARPWL DRWEDGVREH AYGREGGEGM
TMRVPEGHVH LGPRGEGVDG EEQGQEHPHL GLETGPHGTE GPGEADGQGQ RTDLSPTLMG
EQQPEPPSTP PRRVRSPDTP GVLGEPGSPR TPVHSPEPYS PRTPYSPNLA GSPSPQTPRS
PPAPHTPHPH PHPHPHPPPA RPRLADLLHL LQTALAAVDT SQDLWELSAK AERLTREDVE
MREIVMMSER AGAGWGGVGL GV
//
