ID A0A165HI79_9APHY Unreviewed; 708 AA.
AC A0A165HI79;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=LAESUDRAFT_641454 {ECO:0000313|EMBL:KZT11763.1};
OS Laetiporus sulphureus 93-53.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Laetiporus.
OX NCBI_TaxID=1314785 {ECO:0000313|EMBL:KZT11763.1, ECO:0000313|Proteomes:UP000076871};
RN [1] {ECO:0000313|EMBL:KZT11763.1, ECO:0000313|Proteomes:UP000076871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=93-53 {ECO:0000313|EMBL:KZT11763.1,
RC ECO:0000313|Proteomes:UP000076871};
RX PubMed=26659563; DOI=10.1093/molbev/msv337;
RA Nagy L.G., Riley R., Tritt A., Adam C., Daum C., Floudas D., Sun H.,
RA Yadav J.S., Pangilinan J., Larsson K.H., Matsuura K., Barry K., Labutti K.,
RA Kuo R., Ohm R.A., Bhattacharya S.S., Shirouzu T., Yoshinaga Y.,
RA Martin F.M., Grigoriev I.V., Hibbett D.S.;
RT "Comparative Genomics of Early-Diverging Mushroom-Forming Fungi Provides
RT Insights into the Origins of Lignocellulose Decay Capabilities.";
RL Mol. Biol. Evol. 33:959-970(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; KV427606; KZT11763.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A165HI79; -.
DR STRING; 1314785.A0A165HI79; -.
DR InParanoid; A0A165HI79; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000076871; Unassembled WGS sequence.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17978; DEXHc_DHX33; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF118; ATP-DEPENDENT RNA HELICASE DHX33; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KZT11763.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000076871}.
FT DOMAIN 74..252
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 274..452
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 708 AA; 77646 MW; A2516F32D537AB4A CRC64;
MNVSDDDLEV KKGSRVQNSS LKNAQSTPRK PSFETRKKAR VDTPGKNHAS GTKAALIMEQ
RKDLPIASGK EALVEVILEH DVTILIGETG SGKTTQVPQY LLESGIAGQG MIAVTQPRKV
AATSLAARVA AEQNGSVGGV VGYSVRFNEA SSDQTRIKYV TDGMLVRELL GDPLLSRYSV
IIIDEAHERT LRTDLLITNL KSIQKKRNSP SDAKGKGSAA KMNPLKIVIM SATLDAEKFS
RFYDNAKIVY VKGRQHPVTI FHTSAGQPDY VDSALRTFFQ IHTDQPSGDV LIFLPGQEDI
ESLEKSIKIY ADRLPKDSPG ITTCPMYAAL PPNQQGRIFT PTPPNTRKCI LATNIAETSI
TIPGIKYVID TGKCKEKRYI VRDAGSGFDT LLTKDITKSS AMQRAGRAGR EGSGFCFRLY
TEEAFNAMPD SAEPEIRRCA LASSLLQLKC LGQDLEELDF MDEPDAGAIV AAALKSLYLL
GALDSKKRLT QLGRAMAVLP LEPNLARAIV ASRELGCTLE VIDIVSVLSA SSKPFFDSVG
DREAGLEARQ KFRHRSGDHM TILNVVRAYQ EIAKAESKNG RRKWCQKQFL NERCLLEAQD
VKNQLREVCA RMGIDWKVSC GDQEQNVLKS LVRGLVQHAA FLQPDGSYKQ LMGPSIVKIH
PSSSLCDKKV PAIIFDELVY TSNIYARGVS AVPRSYIAEV PVLNQKSV
//
